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Neuronal structure and Dynamics, Brain plasticity

Contributed by: Interdisciplinary European Academy of Sciences - Academie Europeenne Interdisciplinaire des Sciences

From 2016-12-05 to 2016-12-05, France
Conference in French : Cannabinoid-induced actomyosin contraction shapes neuronal structure and connectivity at multiple spatiotemporal scales
by : Professor Szolt LENKEI
Place : Maison de l'AX, 5 rue Descartes, F-75005 Paris, France
Date : December 5, 2016
Time : 17:00
Abstract:
We have recently shown rapid cannabinoid-induced remodeling of the neuronal actomyosin cytoskeleton with potentially important roles in developmental brain wiring. Our recent results indicate a role for cannabinoid-induced actomyosin contraction also in synaptic plasticity. Completing our in vitro and ex vivo tools, we participate in the interdisciplinary development of a new in vivo imaging modality, functional fast brain ultrasound (fUS), to investigate the role of cannabinoid-induced actomyosin contraction in the structure and connectivity of the living rodent brain. fUS offers fMRI-like functional imaging, both in anaesthetised and awake animals, with spatio-temporal resolution gains of several orders of magnitude as compared to fMRI.

Recent relevant publications:
Renard et al. Eur Neuropsychopharmacol. 2016
Chatelin et al. Journal of Cerebral Blood Flow and Metabolism, 2016
Errico et al. Nature, 2015
Roland et al. eLife, 2014
Osmanski et al. Nature Communications, 2014

Contributor

Organisation

    Interdisciplinary European Academy of Sciences - Academie Europeenne Interdisciplinaire des Sciences
    rue Descartes 5
    F-75005 Paris
    France
    Website

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Related information

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Countries

  • France

Keywords

Neuronal structure
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