A closed-loop neural prosthesis for dizziness suppression

The main goal of the CLONS project is to develop suitable technological solutions to increase the quality of life of people affected by vestibular disorders. Toward this aim, an innovative closed-loop sensory neural prosthesis will be developed and tested in animal models and in selected humans. This neural prosthesis will be able to restore vestibular information by stimulating the semicircular canals thanks to the information provided by inertial sensors embedded in a device attached to the head and donned by the user. The effectiveness of the CLONS neural prosthesis will be tested in animal models. The possibility of carrying out chronic implantations in selected human volunteers will be also verified during the final phase of the project by looking at the results achieved in animals in terms of biocompatibility of the implants and significant improvement of the sensory-motor performance.Project outcomes will allow the achievement of increased neuroscientific, clinical, and technological knowledge, guidelines for the development of other bidirectional interfaces and neural prostheses, as well as roadmaps for future development of hybrid bionic systems.