CORDIS Archive

Chronological classification

5th Framework programme: 1998-2002

Cellular studies

• Induction, repair and biological consequences of DNA damages caused by radiations of various qualities (RADNA)
• Mechanisms of formation of ionizing radiation-induced chromosomal aberrations (CHROMOSOME STRUCTURE)
• The molecular basis of DNA damage response and radiosensitivity (DNA DAMAGE RESPONSES)
• Genomic instability and radiation-induced cancer (RADINSTAB)
• Telomere instability and the formation and transmission of radiation induced DNA damage (TELORAD)

Radiation tumorigenesis: mechanisms and pre-disposition

• The mechanisms and genetics of radiation tumorigenesis (MAGELLANS)
• Genetic susceptibility to radiation carcinogenesis (GENRAD)
• Identification and isolation of susceptibility genes involved in radiation-induced cancer in humans (SUS GENES IN RAD CAR)
• Chernobyl, an integrated pan-European study: morphology, oncogenes, DNA repair and outcome in radiation carcinogenesis (CHIPS)
• The newly independent states Chernobyl tumour bank - An international scientific resource (NISCTB)

Modelling radiation cancer risk

• Biophysical models for the induction of cancer by radiation (LOW DOSE RISK MODELS)

Diagnosis/treatment of cancer and radiation injury

• Novel approaches to the treatment of radiation accident patients (NAIMORI)

Four projects started late 2002

Genetic factors predisposing to radiation induction of mutation during early gestation:

the role of DNA repair and cell cycle control (GEMRATE); Radiation specific DNA non-double strand break lesions: repair mechanisms and biological effects (NON-DSB-LESIONS); Genetics of predisposition to radiation-induced cancer of the thyroid (GENRAD-T); Genetic pathways for the prediction of the effects of irradiation ? European normal and tumour tissue bank (GENEPI-ENTB).