Fundamental knowledge and basic tools for Functional Genomics in all organisms

Programme objectives:
To foster the basic understanding of genomic information, by developing the knowledge base, tools and resources needed to decipher the function of genes and gene products relevant to human health and to explore their interactions with each other and with their environment.
The involvement of SMEs is encouraged in this area.

Research actions:

• Gene expression and proteomics to enable researchers to better decipher the functions of genes and gene products as well as to define the complex regulatory networks that control fundamental biological processes. Research will focus on:
  
  
• Structural genomics to enable researchers to determine, more effectively and at a higher rate than is currently feasible, the 3-D structure of proteins and other macromolecules, which is important for elucidating protein function and essential for drug design. Research will focus on:
  
  
• Comparative genomics and population genetics to enable researchers to use well characterised model organisms for predicting and testing gene function and to take full advantage of specific population cohorts available in Europe to determine the relationship between gene function and health or disease. Research will focus on:
  
  
• Bioinformatics to enable researchers to access efficient tools for managing and interpreting the ever increasing quantities of genome data and for making it available to the research community in an accessible and usable form. Research will focus on:
  
  
• Multidisciplinary functional genomics approaches to basic biological processes to enable researchers to study fundamental biological processes by integrating the above innovative approaches. Research will focus on:
  

Call topics utilising CA/SSA

Call topics for SME-STREPS