ERC-Proof of Concept-2016 ObjectivesFrontier research often generates unexpected or new opportunities for commercial or societal application. The ERC Proof of Concept Grants aim to maximise the value of the excellent research that the ERC funds, by funding further work (i.e. activities which were not scheduled to be funded by the original ERC frontier research grant) to verify the innovation potential of ideas arising from ERC funded projects. Proof of Concept Grants are therefore on offer only to Principal Investigators whose proposals draw substantially on their ERC funded research.Ethical PrinciplesAll proposals will be subject to ethics review as with proposals for the ERC's frontier research grants.Eligibility CriteriaEligible Principal InvestigatorAll Principal Investigators in an ERC frontier research project, that is either on going or has ended [[Where the duration of the project fixed in