Objective
"Plant architecture is largely determined by branching patterns in the shoot and root systems. Shoots of seed plants, such as the model plant Arabidopsis thaliana, branch via lateral bud outgrowth, where branches are patterned along the stem at the base of a leaf. Roots branch laterally from an internal cell layer surrounded by differentiated tissues, at a distance from the root tip. Despite the differences in ontogeny and the divergent evolutionary origin of root and shoot lateral branches, both processes are controlled by the three redundantly-acting AP2-domain containing transcription factors PLETHORA3, 5 and 7 (PLT3,5,7). These proteins control phyllotaxis, the pattern of lateral organs in the shoot, and rhizotaxis, the spacing of lateral roots. Although the phytohormone auxin is known to be intimately involved in both phyllotaxis and rhizotaxis, the PLT3,5,7 module represents the first genetic element to be implicated in control of both processes. Thus, the goal of this proposal is to illuminate the genetic network surrounding PLT3,5,7 gene activity in both the shoot and root contexts. Early results suggest that auxin lies both upstream and downstream of PLT action, pointing to a positive feedback loop which could be at the heart of a pattern generating system. To investigate this network further, genes surrounding PLT action will be identified using genetic, bioinformatic and biochemical strategies. Physical and genetic interactions will place these genes in a genetic hierarchy. Dynamic expression of these genes in living shoots and roots will be monitored using real-time confocal microscopy, and changes in the network dynamics will be observed in plt mutants and in auxin manipulation experiments. The results from this project will illuminate the similarities and differences between these two PLT-bases patterning pathways and will be of interest to developmental, computational and evolutionary biologists alike."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences evolutionary biology
- natural sciences physical sciences optics microscopy confocal microscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
6708 PB Wageningen
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.