Objective Alzheimer's dementia (AD) is one of the most common brain diseases in the elderly. Dementias pose a major health problem in European countries, with currently 5.7 million affected dementia patients in the EU25. Currently no curative therapies are available for these dementias, however, first disease-modifying treatment strategies like Abeta-immunisation have entered clinical trials. These novel treatments will be most effective if they are offered at a very early dementia stage. However, the reliable clinical differential diagnosis of very early dementia stages is not satisfactory. Here, recent research has clearly demonstrated that multiparametric neurochemical dementia diagnostics (NDD) in cerebrospinal fluid (CSF) does improve the early and differential diagnosis of dementias. cNEUPRO will apply advanced proteomic tools to discover novel neurochemical dementia markers (BIOMARKERS) in blood and CSF for the improved early and possibly predictive diagnosis of AD. A predictive dementia diagnosis will support the most effective use of forthcoming preventive therapeutic strategies. Our initiative will establish European SOPs for current neurochemical dementia diagnostics (NDD) and we will establish first NDD reference centres in Portugal and Hungary. A strong methodological impact is put on the quality of pre-analytical sample handling and clinical phenotypyng, which has been neglected in industry-driven discovery studies. cNEUPRO integrates innovative biotech and bio-informatic companies with leading clinical and proteomic dementia research centres. cNEUPRO will also support the discovery of new diagnostic targets and is also promising to identify novel scaffolds for advanced molecular neuroimaging. Accordingly, cNEUPRO will contribute considerably to the welfare, health and quality of life in Europe, and concomitantly it will reinforce the competitiveness of the European biotech industry. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomicsmedical and health sciencesbasic medicineneurologydementiaalzheimer Programme(s) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Topic(s) LSH-2005-2.1.3-8 - Early markers and new targets for neurodegenerative diseases Call for proposal FP6-2005-LIFESCIHEALTH-7 See other projects for this call Funding Scheme STREP - Specific Targeted Research Project Coordinator UNIVERSITÄT DUISBURG-ESSEN EU contribution No data Address Hufelandstrasse 55 Essen Germany See on map Links Website Opens in new window Total cost No data Participants (18) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER France EU contribution No data Address Avenue gaston giraud, 191 Montpellier See on map Links Website Opens in new window Total cost No data GÖTEBORGS UNIVERSITET Sweden EU contribution No data Address Vasaparken Göteborg See on map Links Website Opens in new window Total cost No data VERENIGING VU-WINDESHEIM Netherlands EU contribution No data Address De boelelaan 1105 Amsterdam See on map Links Website Opens in new window Total cost No data UNIVERSITÄTSKLINIKUM ULM Germany EU contribution No data Address Albert-einstein-allee 29 Ulm See on map Links Website Opens in new window Total cost No data UNIVERSITY OF NEWCASTLE UPON TYNE United Kingdom EU contribution No data Address 6 kensington terrace Newcastle upon tyne See on map Links Website Opens in new window Total cost No data MATRIX ADVANCED SOLUTIONS GERMANY GMBH Germany EU contribution No data Address Reitstallstr. 7 Göttingen See on map Links Website Opens in new window Total cost No data UNIVERSIDADE DE AVEIRO Portugal EU contribution No data Address Campus de santiago Aveiro See on map Links Website Opens in new window Total cost No data UNIVERSITY OF SZEGED Hungary EU contribution No data Address Dugonics ter 13 Szeged See on map Links Website Opens in new window Total cost No data MICRODISCOVERY GMBH Germany EU contribution No data Address Marienburger str.1 Berlin See on map Links Website Opens in new window Total cost No data RUHR-UNIVERSITAET BOCHUM Germany EU contribution No data Address Universitaetsstraße 150 Bochum See on map Links Website Opens in new window Total cost No data FARALLONE THERAPEUTICS BV Netherlands EU contribution No data Address Prins hendriklaan 17 Amsterdam See on map Links Website Opens in new window Total cost No data INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE France EU contribution No data Address 101 rue de tolbiac Paris See on map Links Website Opens in new window Total cost No data PROTAGEN AG Germany EU contribution No data Address Otto-hahn-str. 15 Dortmund See on map Links Website Opens in new window Total cost No data UNIVERSITÄTSKLINIKUM ERLANGEN Germany EU contribution No data Address Maximilliansplatz 2 Erlangen See on map Links Website Opens in new window Total cost No data BIOGENES GMBH Germany EU contribution No data Address Köpenicker str.325 Berlin See on map Links Website Opens in new window Total cost No data UNIVERSITY OF EASTERN FINLAND Finland EU contribution No data Address Yliopistonranta 1 Kuopio See on map Links Website Opens in new window Total cost No data HEINRICH HEINE UNIVERSITY OF DUESSELDORF UNIVERSITAETSKLINIKUM Germany EU contribution No data Address Moorenstrasse 5 Duesseldorf See on map Links Website Opens in new window Total cost No data UNIVERSITY OF PERUGIA Italy EU contribution No data Address Piazza dell'universita 1 Perugia See on map Links Website Opens in new window Total cost No data