Objective
Alzheimer's dementia (AD) is one of the most common brain diseases in the elderly. Dementias pose a major health problem in European countries, with currently 5.7 million affected dementia patients in the EU25. Currently no curative therapies are available for these dementias, however, first disease-modifying treatment strategies like Abeta-immunisation have entered clinical trials. These novel treatments will be most effective if they are offered at a very early dementia stage. However, the reliable clinical differential diagnosis of very early dementia stages is not satisfactory. Here, recent research has clearly demonstrated that multiparametric neurochemical dementia diagnostics (NDD) in cerebrospinal fluid (CSF) does improve the early and differential diagnosis of dementias.
cNEUPRO will apply advanced proteomic tools to discover novel neurochemical dementia markers (BIOMARKERS) in blood and CSF for the improved early and possibly predictive diagnosis of AD. A predictive dementia diagnosis will support the most effective use of forthcoming preventive therapeutic strategies. Our initiative will establish European SOPs for current neurochemical dementia diagnostics (NDD) and we will establish first NDD reference centres in Portugal and Hungary. A strong methodological impact is put on the quality of pre-analytical sample handling and clinical phenotypyng, which has been neglected in industry-driven discovery studies. cNEUPRO integrates innovative biotech and bio-informatic companies with leading clinical and proteomic dementia research centres. cNEUPRO will also support the discovery of new diagnostic targets and is also promising to identify novel scaffolds for advanced molecular neuroimaging. Accordingly, cNEUPRO will contribute considerably to the welfare, health and quality of life in Europe, and concomitantly it will reinforce the competitiveness of the European biotech industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-LIFESCIHEALTH-7
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
ESSEN
Germany
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Participants (18)
MONTPELLIER
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GÖTEBORG
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AMSTERDAM
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ULM
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NEWCASTLE UPON TYNE
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GÖTTINGEN
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AVEIRO
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SZEGED
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BERLIN
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BOCHUM
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AMSTERDAM
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PARIS
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DORTMUND
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ERLANGEN
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BERLIN
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KUOPIO
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DUESSELDORF
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PERUGIA
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