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Content archived on 2024-05-30

Psoriatic Arthrtis and Coronary Artery Disease

Objective

Background:
Psoriatic arthritis is a multi-system auto-immune disease that affects approximately 0.15% of European populations. It can result in lost productivity and a decreased quality of life. The skin disease psoriasis is associated with cardiovascular disease. This is also true for rheumatoid arthritis. Initial data suggest an association between psoriatic arthritis and heart disease, but no population based studies exist. We propose a multi-disciplinary study combining advanced information technology and a collaboration between experts in cardiology and rheumatology. The proposed study is population based and addresses an important clinical question.

Objective:
To confirm and quantify the association between psoriatic arthritis and cardiovascular disease in the general population.

Methods:
Detailed population level data are available from the Icelandic Heart Association’s registry of every case of myocardial infarction occurring in the Icelandic population since 1981. We have previously compiled a list of all known cases of psoriatic arthritis in Iceland and propose linking this list to the heart disease registry. We will use statistical techniques including longitudinal data analysis to assess the risk of developing heart disease and cancer. To address confounding we will use two complimentary methods to compare the cardiovascular risk factor profiles of psoriatic arthritis patients to the general population.

Benefits:
The proposed project will improve the understanding of health risks associated with psoriatic arthritis. These risks can be taken into account when caring for these patients. Specifically, lifestyle modification and targeted screening can improve the survival and quality of life of cardiovascular patients.
In addition to the scientific goals, this project will facilitate the reintegration of the applicant into the European and Icelandic research community, while bringing new research techniques and knowledge to the host institution.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2010-RG
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IRG - International Re-integration Grants (IRG)

Coordinator

LANDSPITALI UNIVERSITY HOSPITAL
EU contribution
€ 89 583,33
Address
Eiriksgata 5
101 Reykjavik
Iceland

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Region
Ísland Ísland Höfuðborgarsvæði
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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