Objective
Despite their distinct functions, the nervous and vascular systems share many more similarities and common principles than previously anticipated2. For example, factors involved in the development of the nervous system are also known to regulate blood vessel formation3. Conversely, the key angiogenic factor, vascular endothelial growth factor (VEGF-A, termed from hereon VEGF), as well as other members of its family such as VEGF-C and VEGF-D, and their receptors, are expressed in neuronal cells and participate in processes such as neurogenesis, neuronal migration, axon guidance, dendritogenesis and dendrite maintenance4-10. All these new findings bring up the new concept of an existing Neurovascular link controlling vascular and neurodevelopmental processes.
Despite these initial findings, still little is known about the biology of VEGF or of any other angiogenic factors in neurons, the signaling pathways that they activate and their functional role in neurodevelopment. Thus, this proposal aims to further investigate the role of angiogenic factors and their molecular signaling in neurodevelopment.
Determining how angiogenic molecules influence neuronal wiring, will shed new light in the understanding of the molecular control of neuronal development and the possible causes of neurodevelopmental disorders. Research in this field may suggest new strategies to treat those disorders and to promote axon regeneration after injury or disease.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-CIG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
69117 Heidelberg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.