Objective
"Effectors are used by pathogens as weapons against their hosts. Puccunia striiformis f. sp. tritici (PST) the causal agent of yellow rust, is able to produce and secrete these proteins inside its host, wheat. This disease is responsible of epidemics around the world, including Europe. Even more, two new and aggressive strains of this pathogen may constitute the most expansive and accelerated spread ever of a wheat disease. The discovery and characterization of new effectors of yellow rust will open the door to new and sustainable resistance strategies, which is in accordance to European Union objective of sustainable management of crop pest diseases, that has been founded through the 6th and 7th framework programmes.
I propose the use of state-of-the-art sequencing technology to obtain putative fungal sequences from wheat infected tissues with four PST isolates, and a bioinformatics approach to search, identify, classify and select from these sequences which correspond to putative effectors. Afterwards I propose an innovative and elegant experiment to test whether they are real effectors, monitoring the collapse of effector-transfected protoplasts as a result of gene-for-gene recognition resistance mechanism.
The John Innes Centre, where this project will be carried out, and the nearby The Sainsbury’s Laboratory and Norwich Research Park compose a cluster of excellence and expertise in plant biology and microbiology that have been awarded by these EU programmes. I will take advantage of the multidisciplinary approach of the proposal and of the scientific expertise and training experience of the host to expand my knowledge and boost my career to reach a position of independent researcher.
Finally, the proposed IEF would make a significant contribution to ERA, sharing knowledge and enhancing the integration with other efforts founded by the EU like wheat breeding and genomics, giving more coherence to research in the food safety key area."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology other engineering and technologies food technology food safety
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences biological sciences microbiology
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NR4 7UH NORWICH
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.