Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS
Content archived on 2024-06-18

Integrated Computational Techniques for Non-Target Screening of Environmental Contaminants using High Resolution Mass Spectrometry

Objective

Water is essential for life and the protection of this vital resource is paramount to ensuring quality of life. Millions of chemicals are produced annually and these chemicals, the reactants, by-products and/or transformation products end up at some stage in the water cycle, in potentially toxicologically relevant concentrations. As many of these chemicals remain unidentified, the risk posed to the environment and human health cannot be fully assessed. Current strategies for water monitoring only include a very limited selection of “priority pollutants”, which is insufficient for public and environmental protection. This project aims to improve the identification of unknown chemicals in water samples, using cutting edge analysis techniques (LC-LTQ-Orbitrap-MS(n)) and automated data-processing strategies for compounds detected in any given water sample. Current strategies involving database searching will be explored and optimised to create a user-friendly workflow to streamline identification efforts for routine monitoring applications, where time is the essence. As database searching does not deliver the right answer in many cases, the development of identification strategies based on structure generation will also be a major focus of this work. In this case, all possible molecules are considered, not just those in the database, resulting in a far more complicated workflow. The structure generation strategy will incorporate the latest identification procedures within the environmental and metabolomics fields and will benefit from collaborations with several leading partners in these fields. The outcomes of this study will be applicable not only to environmental and metabolomics approaches but also for pharmaceutical, forensic and medicinal applications.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

You need to log in or register to use this function

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2011-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ
EU contribution
€ 192 622,20
Address
UBERLANDSTRASSE 133
8600 Dubendorf
Switzerland

See on map

Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Other
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data
My booklet 0 0