Objective
"Understanding host-pathogen co-evolution is crucial for the management of infectious diseases, as it is at the root of phenomena such as pathogen emergence, host switch and host range expansion, including the overcoming of host resistance, and the composition and dynamics of ecosystems. Plant diseases, have an important impact on people’s quality of life which can be extended to major health, ecological, socio-economical and political consequences, comparable to the most devastating human or animal diseases. However, fewer methods are available to control plant diseases, particularly those caused by viruses. During the last decades, the research on host-pathogen interactions has been done independently (i) on molecular mechanisms of host resistance to pathogens and pathogen adaptation, and (ii) on theoretical analyses of the population genetics of virulence in pathogen populations, and of the resistance in host populations, resulting in two major models of host-pathogen co-evolution: the gene-for-gene (GFG) and the matching-allele (MA) models. This project aims to bridge the fields of population and molecular biology in order to take the research on host-pathogen interactions beyond the present state of the art by providing experimental evidence based on molecular biology approaches of the predictions of theoretical models widely accepted among pathologists. For this, the evolutionary dynamics of resistance genes to tobamoviruses and potyviruses will be analysed at the local population level in the wild pepper Capsicum annuum var. aviculare populations, the wild ancestor of domestic C. annuum. Dominant resistance to tobamoviruses has the traits of GFG systems, while recessive resistance to potyviruses conforms to a MA system. The proposal seeks to have a holistic view of the evolution of plant-virus interaction using a multidisciplinary approach, and results will contribute to understanding host-pathogen co-evolution within a broader context than plant pathology."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences microbiology virology
- medical and health sciences health sciences infectious diseases
- natural sciences biological sciences evolutionary biology
- natural sciences biological sciences molecular biology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
28040 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.