Objetivo The topics of this joint exchange programme are all related to a specific plant genus of commercial interest and its taxonomy, the propagation and investigation of endangered species of this plant genus, the natural products used in medicine occurring in Digitalis plants, and the isolation, structure elucidation and biological testing of some of the rare but pharmacological relevant cardenolides. Objectives are (1) Taxonomically critical Digitalis species and subspecies will be (re)-examined by molecular taxonomy, using the progesterone 5β-reductase gene as a molecular marker, and chemotaxonomy by cardenolide profiling, using HPLC, (2) plant tissue cultures of endangered Digitalis species will be established and used in plant propagation. Hairy root cultures of selected species will be established for fundamental studies on cardenolide formation, (3) the structures of important cardenolides will be elucidated by NMR and bulk quantities of selected cardenolides will be produced, (4) antiviral and antiproliferative effects of individual cardenolides will be studied. Cardenolides will be screened for their pharmacological profiles (potential and selectivity). The objectives aim at intensifying circumstantial ongoing co-operations and exchange of materials and people in a more reliable and coordinated way. The profiles of expertise of the various partners are complementary and researchers from Turkey, Brazil, Germany and Portugal are involved. Ámbito científico agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulture Programa(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) FP7-PEOPLE-2011-IRSES - Marie Curie Action "International Research Staff Exchange Scheme" Convocatoria de propuestas FP7-PEOPLE-2011-IRSES Consulte otros proyectos de esta convocatoria Régimen de financiación MC-IRSES - International research staff exchange scheme (IRSES) Coordinador FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG Aportación de la UE € 65 100,00 Dirección SCHLOSSPLATZ 4 91054 Erlangen Alemania Ver en el mapa Región Bayern Mittelfranken Erlangen, Kreisfreie Stadt Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Franziska Müller (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (2) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP Portugal Aportación de la UE € 58 800,00 Dirección CAMPO GRANDE EDIFICIO C1 PISO 3 1749 016 Lisboa Ver en el mapa Región Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Tipo de actividad Research Organisations Contacto administrativo Ana Cristina Silva Da Figueiredo (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos BOLU ABANT IZZET BAYSAL UNIVERSITESI Turquía Aportación de la UE € 48 300,00 Dirección GOLKOY KAMPUSU 14280 Merkez Ver en el mapa Región Ege Manisa Afyonkarahisar Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Ekrem Gürel (Prof.) Enlaces Contactar con la organización Opens in new window Coste total Sin datos
