Objective
The increase of overweight and obesity among Europeans is becoming an important health and social issue as overweight people have a higher risk of developing diabetes or cardiovascular disease than normal weight people. The diffusion of the Western diet, rich in energy-dense foods, is one possible cause of weight gain. Grilling, roasting, and frying of foods leads to the formation of Maillard reaction products including non-digestible melanoidins that are primarily found in coffee and bread crust. Melanoidins are structurally similar to vegetable dietary fiber, both are non-digestible dietary components partially fermented in the gut. It is known that dietary fiber is able to trigger short-term satiety through the modulation of gut hormones controlling food intake. The objective of this project is to verify the satiating efficiency of melanoidins. New types of bread enriched with melanoidins from the crust or from coffee will be developed and their effects on short-term satiety will be compared to those elicited by barley beta-glucans-enriched bread and control bread (only crumb, no melanoidins and no dietary fiber). For this purpose a human intervention trial will be performed. In four breakfast sessions, 15 volunteers will consume in a random manner all experimental breads one by one, fill out satiety questionnaires, be submitted to blood drawings at 5 specific time points, and consume an ad libitum lunch 3 h after breakfast. In the rest of the day, they will complete a food diary to assess their 24 h energy intakes. Gut and stress hormones, as well as endocannabinoid concentrations, will be measured in blood samples by Luminex technology and mass spectrometry. Additionally, satiety gene expression in blood samples from 5 subjects at two time points will be measured by a newly developed DNA array. The CHECKMATE-TO-HUNGER project will take advantage of a multidisciplinary approach to clarify mechanisms underlying satiety induced by Maillard reaction products.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology materials engineering fibers
- medical and health sciences clinical medicine endocrinology diabetes
- social sciences sociology social issues
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- medical and health sciences health sciences nutrition obesity
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
80138 Napoli
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.