Synergistic modeling of gene-brain couplings with applications in affective neuroscience

Projektinformationen

SYNEURGY

ID Finanzhilfevereinbarung: 302896

Abgeschlossenes Projekt

Startdatum 1 Juli 2012

Enddatum 30 Juni 2015

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 250 483,20

EU-Beitrag € 250 483,20

Koordiniert durch

Linköping University
Sweden

Ziel

Exploiting cross-modal integration for enhanced power and sensitivity, the recently emerged field of imaging genomics is at the frontline of available tools for identifying genes which influence the neurobiology of human behavior and psychiatric illness. Computational approaches are not, however, up to par with the complexity of the disparate data: there is an urgent need for integrative predictive modeling to overcome the interdisciplinary fragmentation between genomics and neuroimaging to harvest the full potential of the data. The methodological objective of this project is therefore to develop and implement integrative cross-modal algorithms for synergistic modeling of human genetic effects on brain responses patterns. To this end, the project will use tools from machine learning which allow powerful, multivariate, generic, data-driven, general purpose predictive modeling. Application side, the project will target the neurobiology of affective behavior and disorders through modeling gene-brain correlates in a population of individuals carrying a mutation resulting in atypical sense of affective touch and insensitivity to pain. Employing a cross-modal, multi-disciplinary approach, integrating genomics, neuroimaging and engineering at the frontier of neuroscience research, the project enables holistic modeling of genetic correlates of human behavior and psychiatric conditions revealing new therapeutic avenues. The project embodies the work program by providing excellent international, multi-disciplinary, cross-modal academic training, establishing a solid yet dynamic basis for a prolific long-term scientific career for the Fellow. The project will increase the attractiveness of the ERA through promoting the world-leading Swedish neurobiology research and facilitate mutually beneficial relations with Singapore; moreover, the project will aid the ERA in benefiting from rather than competing with the growing science and technology investments in Asia.

Wissenschaftliches Gebiet

• natural sciences › biological sciences › neurobiology
• natural sciences › biological sciences › genetics › mutation
• natural sciences › computer and information sciences › artificial intelligence › machine learning

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2011-IOF - Marie Curie Action: "International Outgoing Fellowships for Career Development"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2011-IOF
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IOF - International Outgoing Fellowships (IOF)

Koordinator

Linköping University

Kontakt Verwaltung

Avefeldt Gunilla (Mrs.)

• EU-Beitrag: € 87 008,40
• Adresse: CAMPUS VALLA ; 581 83 Linköping ; Schweden
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten

Beteiligte (1)

GOETEBORGS UNIVERSITET

Beteiligung beendet

Schweden

Kontakt Verwaltung

Ellen Rydberg (Dr.)

• EU-Beitrag: € 163 474,80
• Adresse: VASAPARKEN ; 405 30 Goeteborg
• Region: Södra Sverige › Västsverige › Västra Götalands län
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten