Objective
Occupying up to 90% of the volume of an individual cell, the vacuole is the most prominent compartment of the plant cell. The plant vacuoles are responsible for the transport and accumulation of nutrients, carbohydrates and storage proteins, and their function directly impacts plant yield and nutritional value. In plants, two types of vacuoles with different properties have been identified, the lytic vacuoles that carry out many of the same processes as yeast and mammalian lysosomes such as the breakdown and recycling of cellular components, and the protein storage vacuoles (PSVs) that carry out an additional number of plant-specific functions such as the accumulation and sequestration of toxic compounds and the storage of defense molecules such as alkaloids, phenolics, and protease inhibitors. Although components of the trafficking machinery to lytic vacuoles are well defined and appear to be conserved in yeast and multicellular eukaryotes, very little is known about the cellular machinery and regulatory mechanisms required for transport of vacuolar soluble proteins to the PSV. To define the genetic element and regulatory mechanisms required for the accumulation and mobilization of reserves into the storage vacuoles we will use a systems biology approach that combines computational tools (algorithm development), analytical tools (Proteomics), and a set of biological tools from the biochemistry, molecular biology and cell biology fields (Classical genetics, microscopy, and molecular biology) in the model plant Arabidopsis thaliana. The basic knowledge derived from this research will allow the design of experimental approaches aimed at improving biomass, production yield, and fitness through the enhancement of various vacuolar reserves in crops of economical interest.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences biological sciences cell biology
- natural sciences physical sciences optics microscopy
- natural sciences biological sciences biochemistry biomolecules carbohydrates
- natural sciences biological sciences molecular biology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
29016 MALAGA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.