Objectif The impressive progress in synthetic organic chemistry during the past century has propelled this discipline to its current central place as the key enabling technology in the physical and life sciences. Despite these remarkable advances, our ability to construct molecules of even moderate structural complexity remains unsatisfactory, since these syntheses continue to be inefficient, rely on a high number of reaction steps, and generate undesired, often toxic waste. These features led to the general need for greener transformations that will stimulate the development of more sustainable chemical industries.Conventional approaches in synthetic organic chemistry make use of starting materials displaying specific functional groups, the installation of which results in costly reaction and purification steps. Therefore, an environmentally-sound and economically-attractive alternative is represented by the direct functionalization of ubiquitous carbon-hydrogen (C–H) bonds. These transition-metal-catalyzed processes avoid prefunctionalization strategies, prevent the formation of undesired waste, and thus enable an overall streamlining of organic synthesis.While considerable recent progress has been accomplished in C–H bond functionalizations, available methodologies continue to be limited in scope, and key challenges are still to be overcome. Establishing a full set of sustainable C–H bond functionalization protocols will undeniably have a tremendous impact on various applied areas, such as drug discovery, chemical industries or material sciences. Champ scientifique medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural scienceschemical sciencesorganic chemistry Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) ERC-SG-PE5 - ERC Starting Grant - Materials and Synthesis Appel à propositions ERC-2012-StG_20111012 Voir d’autres projets de cet appel Régime de financement ERC-SG - ERC Starting Grant Institution d’accueil GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS Contribution de l’UE € 1 499 338,00 Adresse WILHELMSPLATZ 1 37073 Gottingen Allemagne Voir sur la carte Région Niedersachsen Braunschweig Göttingen Type d’activité Higher or Secondary Education Establishments Chercheur principal Lutz Ackermann (Prof.) Contact administratif Nadja Daghbouche (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS Allemagne Contribution de l’UE € 1 499 338,00 Adresse WILHELMSPLATZ 1 37073 Gottingen Voir sur la carte Région Niedersachsen Braunschweig Göttingen Type d’activité Higher or Secondary Education Establishments Chercheur principal Lutz Ackermann (Prof.) Contact administratif Nadja Daghbouche (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
