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FULLPHASE

Project reference: 318067
Funded under: FP7-ICT

Fully integrated real time multi-wavelength photoacoustics for early disease detection [Print to PDF] [Print to RTF]

From 2012-10-01 to 2016-09-30

Project details

Total cost:

EUR 11 381 918

EU contribution:

EUR 7 100 000

Coordinated in:

Netherlands

Call for proposal:

FP7-ICT-2011-8

Funding scheme:

CP - Collaborative project (generic)

Fully integrated real time multi-wavelength photoacoustics for early disease detection.

The objective of FULLPHASE is the transition of Photo-Acoustic (PA) imaging from a lab-based technique to a low-cost portable multi-wavelength combined PA and Ultra-Sound (US) system. In order to reach that goal, the FULLPHASE partners offer specific expertise over complementary backgrounds in diode laser technology, laser beam shaping, ultrasound imaging technology, and system integration. The impact of the FULLPHASE system will be shown in oncology, rheumatology and cardio vascular disease.

FULLPHASE will integrate different scientific and technological expertise, for point-of-care early diagnosis, by means of specific knowledge, which will be directed towards: 

  • Multi-wavelength diode laser beam sources with very high pulse powers.
  • Highly efficient diode laser driver.
  • Multi-wavelength diffractive optical beam shaping.
  • Optimal light delivery.
  • PA imaging depth of a few centimetres.
  • Advanced beam forming and temporal resolution.
  • Quantitative functional and structural imaging.
  • In-vitro and ex-vivo verification.
  • Preclinical validation.

Objective

Healthcare at affordable cost is a major challenge with the aging population and the prevalence of chronic disease, supporting the need for early diagnosis and optimal treatment monitoring already at the level of the General Practitioner. Within this context, research on diagnostic imaging has recently gone hand in hand with the notion that the combination of various modalities is the key step towards improved diagnostic accuracy.<br/>Ultrasound (US) is promising for point-of-care imaging because, of its real-time display, high temporal and spatial resolution, low cost and safe of use. However, it falls short in terms of functional imaging. On the other hand optical techniques provide high contrast by the pronounced optical absorption variations in tissue and functional imaging when probing spectral features, but optical scattering limits the resolution of purely optical methods. Photoacoustic imaging (PA) shows optical absorption at ultrasound resolution via thermo-elastically generated ultrasound.<br/>The objective of FULLPHASE is the transition of PA imaging from a lab-based technique to a low-cost portable multi wavelength combined PA and US system. In order to reach that goal, the FULLPHASE partners offer specific expertise over complementary backgrounds in diode laser technology, laser beam shaping, ultrasound imaging technology, and system integration. The impact of the FULLPHASE system will be shown in oncology, rheumatology and cardio vascular disease.<br/>The ultrasound technology market is currently dominated by few large companies mainly located in the US, Europe and Asia. The FULLPHASE low cost portable PA and US medical system for early disease detection that will be commercialised by ESAOTE Europe will give the involved research institutes and the industrial partner's access to new know-how and new markets. It will stimulate the implementation of a new imaging concept that will create a change in health care delivery.

Related information

Documents and Publications

Open Access

Coordinator

ESAOTE EUROPE B.V.
Netherlands
PHILIPSWEG 1
MAASTRICHT, Netherlands
Administrative contact: Peter Brands
Tel.: +31 43 3824 600
Fax: +31 43 3824 601
E-mail

Participants

UNIVERSITAET BERN
Switzerland
Hochschulstrasse
BERN, Switzerland
Administrative contact: Martin Frenz
Tel.: +41316318943
Fax: +41316313765
E-mail
OSRAM OPTO SEMICONDUCTORS GMBH
Germany
LEIBNIZSTRASSE
REGENSBURG, Germany
Administrative contact: Stefan Schroff
Tel.: +49 941 850 1622
Fax: +49 941 850 444 1622
E-mail
RUHR-UNIVERSITAET BOCHUM
Germany
Universitaetstrasse
BOCHUM, Germany
Administrative contact: Georg Schmitz
Tel.: +492343227573
Fax: +492343214872
E-mail
TP21 GMBH
Germany
Tuerkenstrasse
SAARBRUECKEN, Germany
Administrative contact: Petra Zalud
Tel.: +49 681 390 6719
E-mail
BRIGHTLOOP SAS
France
RUE DE BERRI
PARIS, France
Administrative contact: Pierre Robert-Patterson
Tel.: +33183628618
Fax: +33183629573
E-mail
SILIOS TECHNOLOGIES SA
France
Zi Peynier Rousset, rue Gaston Imbert Prolongée
Peynier, France
Administrative contact: Stephane Tisserand
Tel.: +33 4 42538965
Fax: +33 4 42538959
E-mail
QUANTEL SA
France
AVENUE DU PACIFIQUE
LES ULIS, France
Administrative contact: Olivier Rabot
Tel.: +33169291649
Fax: +33169291669
E-mail
TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
DEN DOLECH
EINDHOVEN, Netherlands
Administrative contact: Rob Debey
Tel.: +31 40 2475135
E-mail
STICHTING ZIEKENHUISGROEP TWENTE
Netherlands
ZILVERMEEUW
ALMELO, Netherlands
Administrative contact: Bernelot Moens
Tel.: +31742905079
Fax: +31 546 69 3552
E-mail
UNIVERSITEIT TWENTE
Netherlands
DRIENERLOLAAN
ENSCHEDE, Netherlands
Administrative contact: Ferdinand Damhuis
Tel.: +31534894019
E-mail
Record Number: 104914 / Last updated on: 2015-06-01