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FULLPHASE

Project ID: 318067
Funded under

Fully integrated real time multi-wavelength photoacoustics for early disease detection

From 2012-10-01 to 2016-09-30, closed project | FULLPHASE Website

Project details

Total cost:

EUR 11 381 918

EU contribution:

EUR 7 100 000

Coordinated in:

Netherlands

Call for proposal:

FP7-ICT-2011-8See other projects for this call

Funding scheme:

CP - Collaborative project (generic)

Description

Fully integrated real time multi-wavelength photoacoustics for early disease detection.

The objective of FULLPHASE is the transition of Photo-Acoustic (PA) imaging from a lab-based technique to a low-cost portable multi-wavelength combined PA and Ultra-Sound (US) system. In order to reach that goal, the FULLPHASE partners offer specific expertise over complementary backgrounds in diode laser technology, laser beam shaping, ultrasound imaging technology, and system integration. The impact of the FULLPHASE system will be shown in oncology, rheumatology and cardio vascular disease.

FULLPHASE will integrate different scientific and technological expertise, for point-of-care early diagnosis, by means of specific knowledge, which will be directed towards: 

  • Multi-wavelength diode laser beam sources with very high pulse powers.
  • Highly efficient diode laser driver.
  • Multi-wavelength diffractive optical beam shaping.
  • Optimal light delivery.
  • PA imaging depth of a few centimetres.
  • Advanced beam forming and temporal resolution.
  • Quantitative functional and structural imaging.
  • In-vitro and ex-vivo verification.
  • Preclinical validation.

Objective

Healthcare at affordable cost is a major challenge with the aging population and the prevalence of chronic disease, supporting the need for early diagnosis and optimal treatment monitoring already at the level of the General Practitioner. Within this context, research on diagnostic imaging has recently gone hand in hand with the notion that the combination of various modalities is the key step towards improved diagnostic accuracy.
Ultrasound (US) is promising for point-of-care imaging because, of its real-time display, high temporal and spatial resolution, low cost and safe of use. However, it falls short in terms of functional imaging. On the other hand optical techniques provide high contrast by the pronounced optical absorption variations in tissue and functional imaging when probing spectral features, but optical scattering limits the resolution of purely optical methods. Photoacoustic imaging (PA) shows optical absorption at ultrasound resolution via thermo-elastically generated ultrasound.
The objective of FULLPHASE is the transition of PA imaging from a lab-based technique to a low-cost portable multi wavelength combined PA and US system. In order to reach that goal, the FULLPHASE partners offer specific expertise over complementary backgrounds in diode laser technology, laser beam shaping, ultrasound imaging technology, and system integration. The impact of the FULLPHASE system will be shown in oncology, rheumatology and cardio vascular disease.
The ultrasound technology market is currently dominated by few large companies mainly located in the US, Europe and Asia. The FULLPHASE low cost portable PA and US medical system for early disease detection that will be commercialised by ESAOTE Europe will give the involved research institutes and the industrial partner's access to new know-how and new markets. It will stimulate the implementation of a new imaging concept that will create a change in health care delivery.

Related information

Documents and Publications

Coordinator

ESAOTE EUROPE B.V.
Netherlands

EU contribution: EUR 933 156


PHILIPSWEG 1
6227AJ MAASTRICHT
Netherlands
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Peter Brands
Tel.: +31 43 3824 600
Fax: +31 43 3824 601

Contact the organisation

Participants

UNIVERSITAET BERN
Switzerland

EU contribution: EUR 849 309


HOCHSCHULSTRASSE 6
3012 BERN
Switzerland
Activity type: Higher or Secondary Education Establishments
Administrative contact: Martin Frenz
Tel.: +41316318943
Fax: +41316313765

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TP21 GMBH
Germany

EU contribution: EUR 283 401


LUISENSTRASSE 14
10117 BERLIN
Germany
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Petra Zalud
Tel.: +49 681 390 6719

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RUHR-UNIVERSITAET BOCHUM
Germany

EU contribution: EUR 479 974


UNIVERSITATSSTRASSE 150
44801 BOCHUM
Germany
Activity type: Higher or Secondary Education Establishments
Administrative contact: Georg Schmitz
Tel.: +492343227573
Fax: +492343214872

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OSRAM OPTO SEMICONDUCTORS GMBH
Germany

EU contribution: EUR 1 154 589


LEIBNIZSTRASSE 4
93055 REGENSBURG
Germany
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Stefan Schroff
Tel.: +49 941 850 1622
Fax: +49 941 850 444 1622

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BRIGHTLOOP SAS
France

EU contribution: EUR 300 398


RUE DE BERRI 8
75008 PARIS
France
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Pierre Robert-Patterson
Tel.: +33183628618
Fax: +33183629573

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QUANTEL SA
France

EU contribution: EUR 875 248


AVENUE DU PACIFIQUE 2BIS
91940 LES ULIS
France
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Olivier Rabot
Tel.: +33169291649
Fax: +33169291669

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SILIOS TECHNOLOGIES SA
France

EU contribution: EUR 288 448


Zi Peynier Rousset, rue Gaston Imbert Prolongée
13790 Peynier
France
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Stephane Tisserand
Tel.: +33 4 42538965
Fax: +33 4 42538959

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STICHTING ZIEKENHUISGROEP TWENTE
Netherlands

EU contribution: EUR 128 337


ZILVERMEEUW 1
7609 PP ALMELO
Netherlands
Activity type: Other
Administrative contact: Bernelot Moens
Tel.: +31742905079
Fax: +31 546 69 3552

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UNIVERSITEIT TWENTE
Netherlands

EU contribution: EUR 951 230


DRIENERLOLAAN 5
7522 ENSCHEDE
Netherlands
Activity type: Higher or Secondary Education Establishments
Administrative contact: Ferdinand Damhuis
Tel.: +31534894019

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TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands

EU contribution: EUR 855 910


GROENE LOPER 5
5612 EINDHOVEN
Netherlands
Activity type: Higher or Secondary Education Establishments
Administrative contact: Rob Debey
Tel.: +31 40 2475135

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