Objective
Scientific understanding of the role and mechanisms of bioactives is fragmented. Research often addresses the theoretical possibility of health improvement effects rather than their real, practical use for everyday diets. Bioactives cannot be considered as discrete chemical compounds and research must focus on bioactive-enriched foods (BEF), if consumer demands for foods delivering appropriate health and wellbeing benefits are to be fulfilled.
PATHWAY, a pan-European interdisciplinary team of 16 life/social scientists and 10 high tech/ food processing SMEs, uniquely addresses the role and mechanisms of action of 3 bioactives (docosahexaenoic acid, β-glucan, anthocyanins, chosen for known/claimed effectiveness in reducing some risk factors of Metabolic Syndrome (MS), enriching 3 different widely-consumed food matrices (dairy-, bakery-, egg products). Critical evaluation of bioactive-food matrix interactions and determining the extent of synergies between the 3 bioactives are key elements of PATHWAY.
PATHWAY will determine the impact of BEF on physiologically-relevant MS (a risk factor for many diseases) endpoints and deliver a better understanding of the role and mechanisms of action of the 3 bioactives and BEF. Parallel in vitro/in vivo studies will enable selection of robust biomarkers by advanced omics techniques.
Deliverables will include BEF and generic protocols, best practices and guidelines for planning dietary interventions, and guidance to SMEs for producing health-promoting BEF and for submitting convincing health claim dossiers to EFSA; the latter will be greatly facilitated by one SME partner who has submitted 3 successful dossiers. PATHWAY guidelines will be generic and will apply to a wide range of bioactives and BEF.
Impact will be optimised across Europe by targeted dissemination to industry (especially SME), consumer and S&T stakeholders. Young people will be trained in a stimulating interdisciplinary, trans-sectoral environment.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- agricultural sciencesanimal and dairy sciencedairy
- medical and health scienceshealth sciencesnutrition
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Call for proposal
FP7-KBBE-2012-6-singlestage
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Coordinator
40126 Bologna
Italy
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Participants (25)
Participation ended
02044 VTT ESPOO
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75007 Paris
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17177 Stockholm
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76131 Karlsruhe
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02150 Espoo
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69120 Heidelberg
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LS2 9JT Leeds
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5230 Odense M
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46980 Paterna Valencia
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63000 Clermont Ferrand
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LS9 7TF Leeds
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35100 İzmir
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1096 Budapest
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1200 Bruxelles / Brussel
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1030 Wien
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1049 Bruxelles / Brussel
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RG6 6BZ READING
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8230 BALATONFURED
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50129 FIRENZE
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44121 FERRARA
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03270 HAUTERIVE
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47359 OLIVARES DE DUERO
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43024 VAROBACKA
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8230 BALATONFURED
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46370 CHIVA
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