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Content archived on 2024-06-18

NEUROACT: A collaborative training program to develop multi-electrode array (MEA) platforms to understand synaptic function and treat diseases of the nervous system

Objective

This project proposes unique research training opportunities by bringing together partners with complementary expertise in engineering, electrophysiology, molecular biology, cellular neuroscience, theoretical neuroscience, and advanced data analysis. Trainees will participate in the design and implementation of novel tools and platforms to advance current understanding of the molecular and microcircuit bases for nervous system function and to develop new drug screening platforms and paradigms for diseases of the nervous system. The platform for electrophysiological studies will use multielectrode array (MEA) substrates, for which unique recording and analysis methods and cellular model systems will be developed. This collaborative endeavor brings together three active and highly talented partners who have proven themselves as rising leaders in their respective research fields. The exchanges between the Belgian academic group and Ayanda will afford research, development and training in advanced data analysis techniques, recording and analysis software, and novel materials for chronic neuron-interfacing electrodes. Collaboration between the academic team at the EPF Lausanne and Ayanda will yield new research and training opportunities to advance bioarray designs, improve their molecular application and detection capabilities, and establish rapid user-friendly protocols allowing the implementation of MEA-based systems to study the roles of individual genes on complex synaptic phenotypes. The mutually beneficial diversity and complementarities of the skills brought together in this collaborative project bodes a successful, productive and long-lasting relationship between its partners and trainees. Importantly, this joint venture addresses important unfulfilled needs for basic science and drug discovery in neurobiology with far-reaching potential benefits to both European industry and health research.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Topic(s)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2011-IAPP
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Funding Scheme

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MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)

Coordinator

UNIVERSITY OF LEICESTER
EU contribution
€ 948 362,00
Address
UNIVERSITY ROAD
LE1 7RH Leicester
United Kingdom

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Region
East Midlands (England) Leicestershire, Rutland and Northamptonshire Leicester
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (2)

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