Objective
A few years ago, the host laboratory has started a new project based on Memory of Chirality and dynamic axial chirality of tertiary aromatic amides and developed a new asymmetric synthesis of quaternary alpha-amino acids by using only the chirality of starting tertiary alpha-amino acid. The host laboratory is also currently working on the development of a new synthesis of enantioenriched non proteinogenic tertiary alpha-amino acid starting from achiral compounds (glycine and aromatic acid) and based on frozen chirality. The good results obtained encouraged them to pursue in this field. The current project consists in further extensions of these methodologies. This project is a great challenge because it is very original in terms of asymmetric synthesis, and in case of success, it would lead to the achievement of absolute asymmetric synthesis of tertiary alpha-amino acids.
First, the projects plans to modify the substrates (to improve if possible the results) and then to extend these methodologies to other electrophiles in order to obtain functionalized quaternary or tertiary alpha-amino acids by aldolisation and conjugate addition. Another extension would be the application to the asymmetric synthesis of biologically active compounds, sphingophungines . Finally, the project plans to use the host laboratory expertise in the synthesis of oxazolidinone with external axial chirality to produce new chiral ligands and use them in asymmetric catalysis.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
91405 ORSAY CEDEX
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.