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Content archived on 2024-06-18

Membrane Protein Nanocrystallography

Objective

Modern structural biology builds upon synergies between lab-bench scale science on the one hand and large scale research infrastructure on the other. NanoMem recognises the transformative opportunities that are created by current X-ray source and detector developments to impact strongly on membrane protein structure, a challenging sub-field of structural biology. We will exploit synchrotron based micro-focus X-ray beams to address challenging diffraction studies from small membrane protein crystals; and embrace the revolutionary possibilities created by X-ray Free Electron Lasers to deliver an entirely new regime of high-resolution serial femtosecond crystallography of membrane proteins.
These developments will place heavy demands on motivated and highly-trained talent. The time is ripe for bringing young scientists into the loop. Nanomem will train the nucleus of a new community spread across Europe that widens the access and use of non-conventional methods to capture membrane protein structures at high resolution. Our interdisciplinary and intersectorial research training work programme incorporates membrane protein production, purification and crystallisation, micro and nano-crystal manipulation, micro-focus diffraction at synchrotron sources, nano-focus diffraction at X-ray free electron lasers, serial femtosecond crystallography, software development, drug design, and commercialisation of the most helpful innovations. On-site scientific training of nine ESRs and one ER with seamless industrial participation will be complemented with training in areas such as intellectual property, communication skills and scientific mentoring. The current major European effort in the construction of new brilliant X-ray sources has to be matched by an investment in nurturing the birth of a scientific community for its exploitation, pushing the limits of our understanding of membrane protein structural biology.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-ITN
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-ITN - Networks for Initial Training (ITN)

Coordinator

GOETEBORGS UNIVERSITET
EU contribution
€ 557 469,26
Address
VASAPARKEN
405 30 Goeteborg
Sweden

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Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (10)

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