Objective The goal of this grant is to introduce grating-based phase contrast enhanced X-ray imaging as a novel diagnostic tool in human medicine. We will first gain fundamental knowledge to master high-energy grating-based phase contrast imaging and develop novel radiological equipment at the demonstrator/prototype level to perform phase contrast enhanced investigation in human patients in-vivo. In a second phase, we will investigate in depth how our novel method applies to a few pivotal medical fields like mammography, vascular- and musculoskeletal diseases. In these areas there is a strong need for radiological investigations with improved density discrimination, specifically for early breast cancer detection, plaques visualization and cartilage, tendons or ligaments imaging. No hospital or clinical infrastructure in the world can perform phase contrast enhanced X-ray radiological investigations: therefore our discoveries will constitute an enormous impact in this field. Fields of science social sciencessociologysocial issuessocial inequalitiesmedical and health sciencesclinical medicineoncologybreast cancer Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-SG-LS7 - Applied life sciences, biotechnology and bioengineering: agricultural, animal, fishery, forestry/food sciences; biotechnology, chemical biology, genetic engineering, synthetic biology, industrial biosciences; environmental biotechnology. Call for proposal ERC-2012-StG_20111109 See other projects for this call Funding Scheme ERC-SG - ERC Starting Grant Host institution EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EU contribution € 428 460,00 Address Raemistrasse 101 8092 Zuerich Switzerland See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Administrative Contact Marco Stampanoni (Prof.) Principal investigator Marco Stampanoni (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Beneficiaries (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Switzerland EU contribution € 428 460,00 Address Raemistrasse 101 8092 Zuerich See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Administrative Contact Marco Stampanoni (Prof.) Principal investigator Marco Stampanoni (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data PAUL SCHERRER INSTITUT Switzerland EU contribution € 1 070 840,00 Address FORSCHUNGSTRASSE 111 5232 Villigen Psi See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Aargau Activity type Research Organisations Administrative Contact Irene Walthert (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data