Obiettivo The aim of this project is to design a stem cell-based therapy to prevent end-stage renal disease caused by reflux nephropathy in children. The two main reasons to focus on this condition are that it is the major cause of kidney failure in children and young adults and secondly, the disease typically takes several years to reach end stage, allowing time for therapies to repair damage kidneys before they become completely non-functional. Recent advances in stem cell science and tissue engineering present an unprecedented opportunity to design a stem cell therapy for this clinical problem.This project will investigate the properties of several different stem cell types (embryonic stem cells, kidney stem cells, amniotic fluid stem cells and mesenchymal stem cells) in order to determine which is most appropriate for the generation of functional kidney tissue. To do this, novel biomaterials will be designed that will provide a substrate both for the generation of kidney progenitor cells and for their transplantation. Campo scientifico medical and health sciencesclinical medicinenephrologymedical and health sciencesmedical biotechnologytissue engineeringmedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicinetransplantationengineering and technologyindustrial biotechnologybiomaterials Programma(i) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Argomento(i) MOBILITY-1.1 - Marie Curie Research Training Networks (RTN) Invito a presentare proposte FP6-2005-MOBILITY-1 Vedi altri progetti per questo bando Meccanismo di finanziamento RTN - Marie Curie actions-Research Training Networks Coordinatore THE UNIVERSITY OF LIVERPOOL Contributo UE Nessun dato Indirizzo The Foundation Building, 765 Brownlow Hill LIVERPOOL Regno Unito Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (5) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto UNIVERSITA DEGLI STUDI DI TORINO. Italia Contributo UE Nessun dato Indirizzo Via Giuseppe Verdi 8 TORINO Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. Germania Contributo UE Nessun dato Indirizzo Hohe Strasse 6 PF 120411 DRESDEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato MEDIZINISCHE UNIVERSITAET WIEN Austria Contributo UE Nessun dato Indirizzo Spitalgasse 23 WIEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato THE UNIVERSITY OF EDINBURGH Regno Unito Contributo UE Nessun dato Indirizzo Old College, South Bridge EDINBURGH Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato ISTITUTO DI RICERCHE FARMACOLOGICHE "MARIO NEGRI" Italia Contributo UE Nessun dato Indirizzo Via Eritrea, 62 MILANO Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato
