Objective
The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:
• Develop a series of mutant alleles for every gene in the mouse genome
• Determine the phenotypic consequences of each mutation
• Identify mouse models for the complete disease spectrum in humans
To further develop and exploit the emerging mouse mutant resource, mouse models must be preserved and made available to the European biomedical research community. To this effect, the Infrafrontier-I3 project brings together the leading European centers for systemic phenotyping of mouse mutants and the European Mouse Mutant Archive network. The Infafrontier-I3 partners aim to meet the future challenges presented by phenotyping, archiving and disseminating mouse models in the ERA as follows:
• Contribute to resource development by archiving of 1215 new mouse mutant lines
• Provide free of charge Transnational Access to mouse production and 1st line phenotyping capacities
• Offer a specialized axenic service to produce, maintain and to distribute germ-free mice
• Provide user friendly accession of Infrafrontier services, extensive manual data curation and cross referencing with other mouse database
• Improve user services by developing novel phenotyping and cryopreservation SOPs and by refining innovative research instrumentation
• Engage with the user community using a wide range of PR activities, a dedicated user meeting and an industry liaison workshop
• Offer state of the art cryopreservation and phenotyping training courses
• Benchmark Infrafrontier services with other major repositories
The comprehensive physical and data resources that will be generated by Infrafrontier-I3 will contribute to link basic biomedical research to medical applications and thereby drive innovation and support the Europe 2020 Strategy.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry
- natural sciences biological sciences genetics mutation
- medical and health sciences basic medicine physiology
- natural sciences mathematics pure mathematics mathematical analysis functional analysis
- natural sciences biological sciences genetics genomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-INFRASTRUCTURES-2012-1-RTD
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
85764 Neuherberg
Germany
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Participants (23)
W1B 1AL LONDON
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00185 Roma
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67404 Illkirch Graffenstaden
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CB10 1SA SAFFRON WALDEN
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16 672 VARI-ATHENS
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171 77 STOCKHOLM
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1067-001 LISBOA
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75794 PARIS
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08193 Cerdanyola Del Valles
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28006 MADRID
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90014 Oulu
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69117 Heidelberg
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38124 Braunschweig
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1165 KOBENHAVN
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142 20 Praha 4
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1210 Wien
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M5T 3H7 Toronto
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75654 PARIS
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69978 Tel Aviv
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1066 CX AMSTERDAM
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12489 Berlin
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3000 LEUVEN
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85764 Neuherberg
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