Objective
Background: Treatment of chronic diseases in the elderly with polypharmacy poses a threat to patient outcome and involves extensive costs. Little evidence exists regarding the benefits of polypharmacy, but rising evidence shows its harmful effects. Several approaches to reduce polypharmacy have been proposed, but none have been evaluated using clinically relevant endpoints.
Aims: Based on a systematic review we will gather current best evidence and develop recommendations to optimize treatment of polymorbid elderly with cardiovascular disease, heart failure, hypertension, atrial fibrillation, diabetes mellitus type 2, musculoskeletal disorders, COPD, and mental diseases. We will then design an electronic decision support (eDS) tool incorporating the recommendations to be applied in primary care. The tool will be evaluated in a randomised controlled trial (RCT) to show that reduction of polypharmacy in the treatment of the target-diseases is beneficial and safe. Using the results of the RCT, the eDS-tool will be optimized and then disseminated for general utilization.
Workplan: The project is scheduled for 4 years and will contain 12 work packages. WP1 comprises management of the project. The evidence regarding treatment of chronic diseases gathered within WP2 will be used to develop the eDS tool and an electronic case report form (eCRF) in WPs 3-4. After recruitment of surgeries and patients, and implementation of the tool in WP 5, the tool will be evaluated within a cluster-randomized controlled trial (WPs 6-10). The results of the RCT will be used to optimize the eDS tool (WP 11) which will then be disseminated (WP 12).
Impact: The project will contribute to the EIP “Active and Healthy Ageing”. It will improve treatments suited to the needs of older people and lower health care costs by promoting standardized care and reducing hospital admissions. The tool will be exploited by one of the partners (Duodecim Medical Publications) to achieve widespread implementation
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine surgery
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- medical and health sciences basic medicine pharmacology and pharmacy adverse drug reactions
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-HEALTH-2012-INNOVATION-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
58455 Witten
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.