Objective
The objective of the proposed collaboration research project is the development of a mass spectrometry-based tissue identification system capable of in-vivo, real-time identification of tissues during surgical and diagnostic interventions.
The underlying Rapid Evaporative Ionization Mass Spectrometry (REIMS) method was developed as the first analytical technique allowing the real-time chemical analysis of biological tissues in surgical environment. It was presented two years ago, and since then it was proven to fulfill all expectations raised, regarding level of tissue differentiation. It is now being experimentally tested in human surgical environment and preliminary results indicate that the method provides a real solution for the long-standing problem of instantaneous intraoperative tissue identification. REIMS technique was developed by Medimass Ltd. in close collaboration with Justus-Liebig-Universität, Gießen.
The aim of the project is to develop a device that is capable of utilising REIMS in the surgical environment by adding a number of applications (surgery and targeted cancer types) that provide relevant information to surgeons during operation.
In order to prove true intrasurgical applicability for a number of uses, the device interface and the surgical tools have to be adapted and extensively tested in real life situations. The result is a surgical device that is capable of providing instant histology information.
The development of dedicated REIMS instrumentation apart, the proposed project also includes the development of a novel, lipidomics-based tissue phenotyping system, which uses the mass spectrometric data for the establishment of diseased or healthy tissue phenotypes. Envisioned phenotyping is based on the comparison of unknown data to a database of authentic REIMS data by utilizing multivariate statistical pattern recognition algorithms. The results will enable even more detailled analysis therfore result in more precise surgical device.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences databases
- medical and health sciences clinical medicine surgery
- natural sciences computer and information sciences artificial intelligence pattern recognition
- natural sciences chemical sciences analytical chemistry mass spectrometry
- natural sciences biological sciences histology
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-HEALTH-2012-INNOVATION-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1033 BUDAPEST
Hungary
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.