Objective
"Heart failure (HF) affects 14 million people in Europe, and this number is forecast to increase to 30 million by 2020. Early diagnosis of HF is essential for successfully addressing underlying causes. However, initial diagnosis is difficult in many situations so that HF is correctly diagnosed in only half of affected patients. Diastolic HF, for example, that accounts for more than 50% of all HF patients, is due to abnormal ventricular stiffness which remains very difficult to diagnose. The characterization of myocardial properties remains today a challenge and there is currently no imaging technique that can assess myocardial stiffness in clinical practice.
In ULTRAECHOCARDIO, a novel ultrafast imaging approach is proposed not only to image myocardial stiffness but also myocardial electromechanical properties and blood flows with high sensitivity. Whereas conventional ultrasound scanners can achieve 100 images/s, ultrafast imaging can perform 100 times faster, up to 10,000 images/s. This ultrafast capability is a breakthrough in cardiac imaging that opens new possibilities, such as imaging tissue and blood motion with high temporal resolution, but also mechanical (shear waves) and electromechanical waves that remain undetectable with conventional techniques. New echocardiographic modalities will be developed based on a unique ultrafast imaging platform: (1) Shear Wave Imaging for quantitative evaluation of myocardial stiffness, (2) Electromechanical Wave Imaging for mapping of electrical activation in the heart and (3) Ultrafast Doppler Imaging for blood flow mapping with high sensitivity. These modalities will be validated on preclinical models with early modifications of myocardial stiffness and electrical disorders. Finally, the clinical impact will be evaluated on patients with diastolic HF, electrical disorder and coronary artery disease. This technology will provide new diagnostic information crucial for early diagnosis of HF and assessment of HF treatment."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine cardiology
- natural sciences physical sciences acoustics ultrasound
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
ERC-2012-StG_20111109
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Host institution
75654 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.