Objective Blood glucose monitoring is important in the care of diabetes mellitus and is presently accomplished via a “finger-stick” in which a lancet is used to prick the finger and withdraw a small amount of blood for testing. The problem with the existing “finger-stick”-devices is that blood sampling is painful, it increases the risk for infections and the test is discontinuous. A method for measuring the status of a diabetes patient continuously is preferred, especially at night when the risk of undetected hypoglycaemia is present. Systems for continuous (non-invasive) blood glucose monitoring show promising results for measuring high blood glucose values (hyperglycaemia). However, these systems are not reliable when it comes to measuring low blood glucose values (hypoglycaemia). This is due to the fact that a small variation in the blood glucose concentration in the “hypo-region” has a great impact on the status of the patient. In this project volatile components emanated from the skin are used to determine the state of diabetes patient; one of these components is acetone. An apparatus to clinically test the relation between the amount of acetone and the state of hypoglycaemia (and the concentration of blood glucose) has to be developed. Clinical tests (clamp tests) will be performed in an (academic)hospital. Furthermore, research has to be performed into the combination of several techniques (e.g. impedance spectroscopy) with skin gas measurements to obtain an overall picture of the status of a diabetes patient. Measurements of acetone permeation through the skin and the use of membranes to protect the sensor and/or to enhance the signal are needed. Sensors need to be developed to miniaturise the system. The ultimate goal is to develop a sensing system capable of measuring the condition of a diabetes patient satisfactory and in addition is able to steer the function of, among others an insulin pump. Fields of science medical and health sciencesclinical medicineendocrinologydiabetesengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural sciencesphysical sciencesopticsspectroscopy Programme(s) FP7-SME - Specific Programme "Capacities": Research for the benefit of SMEs Topic(s) SME-1 - Research for SMEs Call for proposal FP7-SME-2007-1 See other projects for this call Funding Scheme BSG-SME - Research for SMEs Coordinator ALB. VAN GOOL R&D EU contribution € 364 050,00 Address TUBANTIASTRAAT 43A 7521 BL ENSCHEDE Netherlands See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Albert Van Gool (Mr.) Links Contact the organisation Opens in new window Total cost No data Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all SOLIANIS MONITORING AG Switzerland EU contribution € 81 100,00 Address LEUTSCHENBACHSTRASSE 46 8001 ZURICH See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Mario Stark (Mr.) Links Contact the organisation Opens in new window Total cost No data JUKE SYSTEMTECHNIK GMBH Germany EU contribution € 17 400,00 Address TRUMPENSTIEGE 2 48341 ALTENBERGE See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Heinz Juergens (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MEMBRAAN APPLICATIE CENTRUM TWENTE BV Netherlands EU contribution € 6 000,00 Address GAFFELHOEK 19 7546 MT ENSCHEDE See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Antonius Franken (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Bridges Organisatie-Advies Netherlands EU contribution € 30 000,00 Address Boortorenweg 20 7550 AN Hengelo See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Andries G. 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