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Content archived on 2024-06-18

Aerographite as scaffold material for regenerative medicine

Objective

We propose an interdisciplinary project with the objective to explore the feasibility of aerographite as scaffold material for tissue engineering in regenerative medicine with special focus on directed cell growth. Aerographite is a novel carbon based material that consists of a seamless interconnected network of microtubes. The project is motivated by promising developments of related carbon materials (carbon nanotubes and graphene) in biomedical applications. Aerographite is a potential candidate for tissue engineering, as it can be fabricated in a highly controllable manner to create various macroscopic 3-D shapes. Tailored microarchitectures can be realized that offer penetrability and accessibility of surfaces. These features are key factors for 3-D tissue growth. The 2-year project will be realized in three stages: 1. Material characterization and chemical surface modification to impart aqueous compatibility, 2. Biofunctionalization for specific cell adhesion, and 3. Quantification of cell adhesion and growth on functionalized scaffolds. All tasks are highly interdisciplinary and combine aspects of materials science, chemistry, biology and biophysics and medicine as evident in the variety of analytical techniques that will be employed. Aerographite structures and their functionalization will be investigates with Raman spectroscopy, scanning electron microscopy (SEM), scanning probe microscopy (SPM), and contact angle measurements. SPM, confocal fluorescence microscopy and environmental SEM will be used to assess cell growth on aerographite. Biological assays will be applied to evaluate biocompatibility and cytotoxicity. For the success of the project the applicant can profit from her previous collaborations with European research groups and the excellent research environment at the host university. New collaborations and acquisition of new skills and knowledge will complement her scientific profile and enable her to start a junior group in the near future

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
EU contribution
€ 161 968,80
Address
OLSHAUSENSTRASSE 40
24118 Kiel
Germany

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Region
Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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