Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS
Content archived on 2024-06-18

Remote Enantioselective Functionalization of C–H bonds in Saturated Nitrogen Heterocycles

Objective

The development of existing and invention of new synthetic methodologies in recent years has greatly facilitated the preparation of molecules that would once have been considered an insurmountable synthetic challenge. Over the past four decades, the synthetic community has witnessed a tremendous upsurge in the field of transition metal-catalyzed C–C and C–Heteroatom bond forming reactions. The field of C(sp2)–H bond functionalization has grown rapidly over the past decade, providing many new and efficient routes for the synthesis of desirable compounds and a plethora of literature is available including a large number of reviews. In contrast, there are only a handful of reports in the literature where C(sp3)–H bond functionalization is efficiently achieved and field remains largely untouched regarding the development of new and efficient methodologies. However, despite the advances in the field of enantioselective reactions, the use of transition metal catalysts with appropriate and effective chiral ligands is still in its infancy. The overall aim of this project is to develop new chemistry to functionalize the beta-carbon of simple heterocyclic compounds like pyrrolidine and piperidine in enantioselective fashion. Finally we will apply the newly developed catalytic enantioselective C–H functionalization in bioactive natural product/drug molecule synthesis.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

You need to log in or register to use this function

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
EU contribution
€ 221 606,40
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom

See on map

Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data
My booklet 0 0