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Surface modified luminescent and magnetic gold nanoparticles as cellular targeting agents

Objective

The use of nano-sized particles is a new and promising topic in Chemistry, Medicine and Materials Science. Those nanoparticles have applications in many fields, from Computer Science to Medicine and the interest and the money invested for finding new applications grows every
day.

Gold is a very interesting material for designing nanoparticles (AuNPs) for medical applications due to its inertness, stability, spectroscopical properties, capacity for functionalization and biological compatibility. On the surface of AuNPs can be anchored chemical species with interesting properties. Doing this, the properties of the AuNPs can be modulated at will. Hereby we propose a 24 month research project for the design and developing of AuNPs with luminiscent
properties and with potential applications for therapeutic use, drugdelivery, tissue imaging and cellular signalling.

The major aim will be to signal cancer tissues for early detection and treatment of this disease. The surface of the AuNPs will be functionalized with luminiscent species that will target specific types of tissues and cells.

This work will be carried out by Dr. S. Blasco, a young Spanish researcher whohas recently obtained his PhD and was formed as a Supramolecular and Bioinorganic Chemist in Prof. Enrique Garcia-Espana's group in the University of Valencia, Spain. The research work contained in this proposal will be done under the supervision of Prof. T. Gunnlaugsson, a renowned expert in the field.

Call for proposal

FP7-PEOPLE-2012-IEF
See other projects for this call

Coordinator

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
EU contribution
€ 183 504,60
Address
COLLEGE GREEN TRINITY COLLEGE
D02 CX56 DUBLIN 2
Ireland

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Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Deirdre Savage (Ms.)
Links
Total cost
No data