New optical functions for endoscopic capsules

Project Information

SMART PILL

Grant agreement ID: 328490

Project closed

Start date 1 June 2013

End date 31 May 2015

Funded under

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Total cost € 243 847,80

EU contribution € 243 847,80

Coordinated by

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

Objective

The passive endoscopic capsule (EC) was invented a decade ago and has proven a major technological breakthrough in medical technology that has facilitated an unprecedented level of patient-friendly diagnosis of small bowel diseases. The propulsion of commercially available passive ECs is provided by the natural motility of the intestine, known as peristalsis. Moreover, the EC vision system uses only white-light and a CMOS imager that collects the images (2-4 frames per second). Before ingestion of the capsule, an antenna array is taped to the patient’s anterior abdominal wall and connected to a data recorder carried by the patient. This proposal addresses several innovations of the EC that would contribute to this goal.
The first is the use of an active magnetic platform for guiding an EC inside the human body. The system will be composed by an external permanent magnet and inside of the EC is placed a small internal permanent magnet. The remote control of an EC by magnetic field allows the medical doctor to stop, to rotate the EC and to provide detailed images and early detection and diagnosis of the widespread diseases of the gastrointestinal (GI) tract, in particular targeting inflammatory bowel disease (IBD), gastro-esophageal reflux disease (GERD) as well colo-rectal cancers (CRC) and its precursors. Work on this objective in which applicant is involved is already on-going.
The second is the exploration of advanced diagnostic imaging techniques. In addition to the conventional white-light illumination, the goal is to implement: narrow band imaging (NBI) and endomicroscopy (ENM).
Finally, a therapeutic function, photo-dynamic therapy (PDT), which is a technique for clinical treatment of several types of GI cancers, is to be integrated in EC.
The active EC envisaged is a genuine smart pill and will operate with two domes (front and back), the front dome with white light LEDs, NBI and PDT functions and the back dome of the capsule dedicated to the ENM function.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• medical and health sciences › clinical medicine › gastroenterology › inflammatory bowel disease
• medical and health sciences › clinical medicine › oncology › colorectal cancer
• engineering and technology › medical engineering › diagnostic imaging

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Programme(s)

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Topic(s)

• FP7-PEOPLE-2012-IEF - Marie-Curie Action: "Intra-European fellowships for career development"

Call for proposal

FP7-PEOPLE-2012-IEF
See other projects for this call

Funding Scheme

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

TECHNISCHE UNIVERSITEIT DELFT

• EU contribution: € 243 847,80
• Address: STEVINWEG 1 ; 2628 CN Delft ; Netherlands
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data