Objective
Emerging infectious diseases are increasing worldwide, and have been implicated in population declines and species extinctions. We know that diseases can cause major changes to the genetic composition of host populations through selection and population declines, and in turn that such changes can influence the impact of disease on host populations. We also know that diseases can lead to changes in mate choice behaviour which can alter the population structure, again influencing the impact of disease - yet this has as yet received little attention. This proposal focuses on investigating the interactions between genes, behaviour, and disease, using a model system of Ranavirus (an EU notifiable disease known to be contributing to amphibian declines) in common frogs (Rana temporaria) in the UK. Transcriptomics will be used to gain an understanding of which genes are involved in the host response in the wild to Ranavirus, and controlled laboratory experiments will be used to determine whether these genes are also involved in offspring survivorship. Sequencing of candidate genes in individuals will be used to examine how genotype influences parental mate choice, and the resulting fitness consequences of mate choice on the offspring will be determined. Furthermore, this proposal provides the foundations for a long-term study on how host genotype changes throughout the progression of an epidemic. As such, this proposal addresses fundamental scientific questions relating to the impact of disease on populations, which is critical for our understanding of the wider evolutionary impacts of disease and so for improving our ability to manage such emerging diseases. In addition, this research will directly improve our knowledge of an important driver of global amphibian declines
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EX4 4QJ Exeter
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.