Objective
Drinking water disinfection, mandatory to provide drinking water free of pathogens, is associated with the formation of disinfection by-products (DBPs) that have been linked to public health concerns. Drinking water chlorination produces a wide range of toxic DBPs, only a fraction of which have been identified let alone characterised for their toxic potential. Bioanalytical tools should complement chemical analysis for a comprehensive risk assessment to assure that unidentified DBPs are also captured. In vitro bioassays will enable the detection of mixture effects caused by known and unknown transformation products. However, many DBPs are volatile and polar and thus cannot be evaluated with current methods. After implementation and validation of improved extraction and dosing techniques, my goal in the proposed project is to develop a screening tool that combines cell based bioassays indicative of relevant human health endpoints with chemical analysis to identify toxicologically relevant DBPs. The combination of bioanalytical assessment with sophisticated state-of-the-art chemical analysis will provide a guidance scheme for an effect directed identification of toxicologically relevant transformation products formed during advanced water treatment processes. This aims not exclusively at single compounds but also at substance groups or toxicophores. The establishment of applicable bio-analytical screening tools will enable the toxicological monitoring of advanced treated waters and allow the evaluation of pre- and post-treatments for by-product mitigation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health
- engineering and technology environmental engineering water treatment processes drinking water treatment processes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IOF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
8600 Dubendorf
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.