Objective
Reactive oxygen species (ROS) are important modulators of plant development and they accumulate in tissues upon various kinds of abiotic stresses imposed by e.g. elevated temperature or drought. ROS are also intimately linked to programmed cell death (PCD). Cellular ROS activity is controlled by a large cohort of ROS forming and scavenging enzymes, signalling proteins and transcription factors that together constitute an intricate ROS functionality network that balances growth against the negative impact of environmental stress. A detailed understanding of plant ROS biology is thus of great agronomic importance. Previously, a novel mutant, called atr7, was isolated from Arabidopsis thaliana and shown to display a remarkable tolerance to oxidative stress-inducing agents such as paraquat or the catalase inhibitor aminotriazole. The ATR7 gene has been isolated recently, however knowledge about the function of its encoded protein, its mode of action, cellular localization, and its potential interaction partners remains very limited so far. In addition, virtually nothing is known about the cellular and stress-specific expression patterns of ATR7 or its integration into signalling networks. The project therefore aims at unravelling the biological role of ATR7. To this end, transgenic plants with altered ATR7 expression levels (knockout, amiRNA and overexpressor lines) will be grown under normal and oxidative stress-eliciting conditions and subjected to comprehensive analyses (including transcriptomics and metabolomics, and others) to identify genes, metabolites, and biochemical pathways likely to be responsible for the acquisition of stress tolerance. An important part of the project will be training of the researcher in modern genomics and metabolomics methods on state-of-the-art instruments available at the host institution. The researcher will then utilize the know-how and practical experience at the newly established Genomics Research Center at his home institution.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
14469 Potsdam
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.