Project description
FET Young Explorers
RiboNets aims at programming cellular networks and community behaviour using newly engineered logical gates that transmit and process information within cells in an innovative way, namely via RNA-based devices.RiboNets wants to develop a newly designed RNA-based toolbox for cellular computing. RNA has three major advantages: (a) RNA turnover is fast thus efficient computing is possible with RNA networks, (b) RNA folding and RNA-RNA interactions can be well predicted, thus, a large number of novel devices can be build, (c) RNA production is energetically cheap, therefore the host cell is not affected by computing. The RiboNet toolbox will be created following a three-step process: (i) rational design and analysis of RNA-based devices on a computer, (ii) selecting best performers in vitro within highly parallel microfluidic reactors and, finally, (iii) integrating and testing them in living cells. The combination of all three layers of analysis, in silico, in vitro and in vivo, is a major point of this proposal. It will allow us to deal with complex regulatory networks and to examine the underlying mechanisms of information transmission and processing within cells.The toolbox developed by RiboNets will provide an outstanding prerequisite for novel designs in synthetic biology and life sciences. The usage of the RiboNet toolbox will result in the creation of RNA-based sensors and RNA-based devices with efficient regulation of engineered metabolic and signalling pathways that will have potential applications in white biotechnology and medicine. For example, RNA-based antibiotics would improve human condition in technological applications, as well as in health, in the future. With RiboNets, a new territory will be explored, shedding light on how RNA networks contribute to cell-to-cell information processing and communication.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences synthetic biology
- engineering and technology electrical engineering, electronic engineering, information engineering information engineering telecommunications telecommunications networks mobile network
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- natural sciences biological sciences genetics RNA
- natural sciences computer and information sciences data science data processing
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-ICT-2013-C
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
40225 Dusseldorf
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.