Objective
While the archaeal domain of life was discovered more than 30 years ago, the biology of archaeal organisms remains to be relatively obscure, especially when compared to that of bacterial and eukaryotic life. Yet, despite the limited knowledge regarding their lifestyle and ecological relevance, evidence is mounting that certain archaea play key roles in global nitrogen and carbon cycles. In addition, archaea share a common branch in the tree of life with the eukaryotes, and have most likely played a prominent role in the emergence of the eukaryotic cell, and thus of complex life. Interestingly, recent ecological surveys have started to reveal a hidden diversity of archaeal life. The exploration of this supposed ‘archaeal dark matter’ might thus hold relevance for a number of fundamental issues and reveal profound insights about the diversity, ecology and evolution of the archaeal domain of life. Unfortunately, characterization of these uncultured lineages is procrastinated by limitations in cultivation techniques and limited availability of genetic tools, urging for the exploration of alternative strategies to do so.
Here I am proposing to utilize a single-cell phylogenomics approach to explore novel archaeal lineages at the genomic level. Habitats hosting novel archaea will be sampled and single-cell genome sequencing will be performed using next-generation sequencing technology. The proposed strategy will result in (1) obtaining a better sampling of archaeal genomes, (2) gaining insight in the evolutionary history of the archaeal domain of life through phylogenomics, and (3) obtaining information regarding the biology and lifestyle of these novel archaeal lineages. This work will dramatically increase the number of archaeal genomes available in public databases for both researchers studying the physiology of archaea in different environments and also for evolutionary biologists tracing the evolutionary history of the three domains of life.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences databases
- humanities history and archaeology history
- natural sciences biological sciences ecology
- natural sciences physical sciences astronomy astrophysics dark matter
- natural sciences biological sciences genetics genomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
751 05 Uppsala
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.