Objective
Plant pathogens devastate crops resulting in yield losses and increasing the use of often unsustainable pesticides. Understanding the basic mechanisms of the plant immune system will increase our ability to successfully combat plant diseases, satisfying the growing needs for sustainable food production, a future challenge for European agriculture.
Cell death has a central role in innate immune responses in both animals and plants. The hypersensitive response (HR) is a plant-specific form of programmed cell death (PCD) occurring at the site of attempted pathogen invasion. A tight regulation of HR is essential in order to avoid unnecessary tissue damage beyond the infection site. However, the signaling pathways leading to HR still remain ill-defined. We have recently shown that Arabidopsis metacaspases, distant homologs of animal caspases, antagonistically control pathogen-triggered HR. However, their precise mode of action, regulation and substrates remain largely unknown. With this project we will use a combination of proteomic, genetic, cell biology and biochemical approaches to dissect the mechanisms underlying PCD control by this family of proteins. Defining the first plant deathosome will be a major breakthrough in plant sciences, moving forward with knowledge that can be directly translated into agronomically relevant species.
We will use a multidisciplinary approach, benefitting from transnational collaborations already established by the candidate with research groups located in Europe and the USA. A Marie Curie International Incoming Fellowship will ensure the continuity of the candidate’s high-impact research at the host institution, an emerging reference center for plant sciences in Spain. Reintegration of the candidate will complement and synergize with the expertise of the host, directly contributing to European excellence.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- agricultural sciences agriculture, forestry, and fisheries agriculture sustainable agriculture
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences cell biology
- natural sciences biological sciences botany
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
08193 Cerdanyola Del Valles
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.