Objective
Unrevealing the rules that govern the surface trafficking and membrane stabilization of neurotransmitter receptors, in particular the NMDAR is crucial for our understanding of several physiopathological brain processes. Over the past few years, scientists have shown that neurotransmitter receptors diffuse inside and out of synapses in cultured neurons using single molecule approaches. These findings drastically changed the way we understand synaptic transmission and adaptation. The proposed project aims to study the surface diffusion of NMDAR in intact hippocampal slices, providing the first functional map of such key receptors in native neuronal networks. Due to the difficulties of imaging single molecules in high background noise tissue, a multidisciplinary approach will be adopted using quantum dots and single walled nanotubes to track single NMDAR neurotransmitters. The success of the project will be a real breakthrough in neurobiology of synapses and in single molecule imaging techniques, conjugating state of the art knowledge in neurosciences and nanophotonics.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- engineering and technology nanotechnology nanophotonics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75794 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.