Objective
The three domains of life on Earth comprise the two groups of prokaryotes Archaea and Bacteria whom distinction notably relies on the chemical composition of cellular membranes. Bacteria generally synthesize phospholipids constituted of non-isoprenoid alkyl chains esterified to glycerol, whereas Archaea synthesize isoprenoid ethers of glycerol. These differences have potential implications in term of ecology and evolution of Bacteria and Archaea and are frequently used as distinguishing marks. Non-isoprenoid diethers of glycerol (non-isoprenoid DGD) constitute an exception to these chemical distinctions as they exhibit an intriguing combination of structural features of Bacteria and Archaea. The physiological role and the mode of formation of these lipids are poorly understood. Remarkably, these compounds have never been observed in mesophilic marine bacteria although they are omnipresent in non-extreme interfaces between the Biosphere and the Geosphere where their origin remains speculative.
This multidisciplinary project aims at investigating in detail the first isolate of marine mesophilic sulphate-reducing bacterium able to produce non-isoprenoid DGD, and at comparing it with other (un)related strains. It relies on the combination of lipidomics (analysis of lipid biomarkers) with microbial ecology and microscopy coupled with spectroscopy (bacterial ecophysiology based on ultrastructure). Results will allow specifying the use of DGD as biogeochemical proxy and clarifying the link between living bacterial structures and the observation of microbial signatures within the sedimentary record. It should also shed light on crucial aspects of microbial ecology and on the evolution of lipid biosynthesis in prokaryotes.
The project is based on preliminary results obtained by the host. Its relevance is supported by complementary expertise in microbiology and microbial ecology (national collaboration) and is strengthened by outstanding international collaboration.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences ecology
- natural sciences biological sciences biochemistry biomolecules lipids
- natural sciences earth and related environmental sciences atmospheric sciences meteorology biosphera
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
69622 Villeurbanne Cedex
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.