Obiettivo In cranio-maxillofacial surgery, large blow-out orbital floor fractures have still mitigated outcomes and improved scaffold solutions are needed. The reconstruction of large bone defects in proximal femur or proximal tibia in orthopaedic surgery is also an enormous challenge due to the requirements for both complex shape and partial load bearing ability. This is the goal of this European and Chinese consortium to apply technologies to create custom-made tissue engineered constructs made of resorbable polymer (PTMC or PLGA) and calcium phosphate ceramic composites specifically designed by integrating 1) imaging and information technologies, 2) biomaterials and process engineering, and 3) biological and biomedical engineering for novel and truly translational bone repair solutions. Advanced solid free form fabrication technologies; precise stereolithography and low melt temperature rapid prototyping will provide the necessary control to create such innovative high resolution medical devices. The use of Chinese Medicine extract, bone anabolic Icaritin which has shown to promote osteogenic differentiation of stem cells and enhance bone healing in vivo, will be a safe and technologically relevant alternative to the intensely debated growth factors. These challenges will advantageously be confronted by a strong Eastern -Western biomaterials collaborative effort. The synergistic collaboration envisioned will allow; 1) comparison and exchange of advanced and commercially relevant biomaterials developed; 2) parallel development of two precise technologies, stereolithography and low temperature rapid prototyping allowing for preparation of custom-made composite scaffolds loaded with unique biologics effectors. The planned personal exchanges, the scientific workshops, the use of a unique IT platform connecting trauma surgeons worldwide with the scientists of the consortium will insure that the flow of knowledge and exchange of exciting findings. Campo scientifico medical and health sciencesclinical medicinesurgeryengineering and technologymaterials engineeringcompositesmedical and health sciencesmedical biotechnologytissue engineeringmedical and health sciencesmedical biotechnologycells technologiesstem cellsengineering and technologyindustrial biotechnologybiomaterials Programma(i) FP7-NMP - Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies Argomento(i) NMP.2013.2.2-2 - Biomaterials: Imaging and rapid precise prototyping technology for custom made scaffolds Invito a presentare proposte FP7-NMP-2013-EU-China Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore UNIVERSITEIT TWENTE Contributo UE € 504 000,00 Indirizzo DRIENERLOLAAN 5 7522 NB Enschede Paesi Bassi Mostra sulla mappa Regione Oost-Nederland Overijssel Twente Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Ferdinand Damhuis (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (3) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto AO-FORSCHUNGSINSTITUT DAVOS Svizzera Contributo UE € 713 720,00 Indirizzo CLAVADELERSTRASSE 8 7270 Davos Platz Mostra sulla mappa Regione Schweiz/Suisse/Svizzera Ostschweiz Graubünden / Grigioni / Grischun Tipo di attività Research Organisations Contatto amministrativo Mauro Alini (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato KUROS BIOSCIENCES BV Paesi Bassi Contributo UE € 387 555,00 Indirizzo PROFESSOR BRONKHORSTLAAN 10 G 48 3723 MB Bilthoven Mostra sulla mappa Regione West-Nederland Utrecht Utrecht Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Joost De Bruijn (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato QUEEN MARY UNIVERSITY OF LONDON Regno Unito Contributo UE € 157 976,00 Indirizzo 327 MILE END ROAD E1 4NS London Mostra sulla mappa Regione London Inner London — East Tower Hamlets Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Ton Peijs (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato