Objective
Anatomic connections between brain areas affect information flow between neuronal circuits. However, such structural connectivity does not coincide with effective connectivity related to the more elusive question “Which areas cause the present activity of which others?”. Indeed effective connectivity depends flexibly on contexts and tasks and must be reconfigurable even when the underlying structural connectivity is fixed. Recently, computational mean-field models of whole-brain networks have reproduced with remarkable accuracy functional interactions in the so-called “resting state”, showing that they emerge spontaneously from the interplay between thalamocortical structure, interaction delays and noise-driven local dynamics.
Beyond the resting state, we will investigate how sensory- or cognitive-driven biases modulate the macro-scale dynamics of a simulated brain. Beyond mean-field approaches, we will model selected brain areas at a micro-scale level of detail, in order to describe correlations in their spiking activity and analyze how they are reorganized by changes in brain state.
More specifically, we will focus on functional interactions between brain areas belonging to the dorsal and ventral attention systems, known to be determinant for the initiation, the maintenance and the reorienting of selective attention. In this context, we will explore how the self-organization of neural activity controls the balance between top-down and bottom-up inter-areal influences, in different attentional conditions. We will then study how emergent dynamic patterns of multi-frequency phase-coherence enable flexible routing of information encoded in spiking activity.
This work will profit of the stimulating environment offered by the Systems Neuroscience Institute in Marseille, in charge of the development of “the Virtual Brain”, a high-performance-computing platform for realistic and potentially clinically-relevant “virtual imaging” experiments.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
13284 Marseille
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.