Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS
Content archived on 2024-05-30

Exploring the Formation and Adaptation of the <br/>Brain Connectome

Objective

Endeavors to explicate the architecture and functional capacities of the human brain confront its vast complexity most pronouncedly when describing the interactions and interconnections of its neuronal processing units. Efforts in this direction gave rise to the notion of connectomics, research investigating large-scale interactions mediated by axonal fibers (structural connections) or characterized by causality or co-activation of distributed domains (functional connections). The processes that shape the connectome into its mature form or the mechanisms that underlie the dynamics of re-organization during disease are yet poorly understood. They are important for both basic research and in a clinical context. The aim of the proposed project is to construct and utilize an image processing framework for studying the dynamically shaping structural and functional brain networks. The project will focus two phenomena that offer insights into related mechanisms from different perspectives: the developing brain during in utero maturation and the re-organizing brain during adaptive processes. The project FABRIC will build on recent advances in fetal functional magnetic resonance imaging techniques including the breakthrough in observing resting state networks in fetuses. Diffusion tractography will be utilized to explore the emergence of large-scale anatomical pathways that presumably render information exchange channels for the forming of functional activity. These observations will be integrated into a temporal atlas of fetal connectome development. In the clinical setting, we will investigate the influence of fetal neurodevelopmental diseases and adult brain tumors on the structural and functional network topology. Ultimately the project will result in insights into the relationship of functional and structural connectivity during development and re-organization, providing for surrogate markers for clinical evaluation, function loss, and neurodevelopmental diseases.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

You need to log in or register to use this function

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
EU contribution
€ 179 137,20
Address
SPITALGASSE 23
1090 Wien
Austria

See on map

Region
Ostösterreich Wien Wien
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data
My booklet 0 0