Objective
Optical imaging tools are in high demand by the biomedical research and clinical communities for applications that greatly impact the life sciences.
The invention of fluorescent molecular tomography (FMT) a decade ago can be considered a breakthrough in optical imaging, as it allows for unprecedented, in-vivo, non-invasive and quantitative 3D imaging of fluorescent probes. However, it has been recently shown than its performance can be greatly improved using a priori information for the tomographic algorithm regarding the distribution of optical parameters in tissue.
Multispectral Optoacoustic Tomography (MSOT) is a new non-invasive medical imaging modality that is able to retrieve the 3D distribution of light energy deposition in small animals in vivo, and not invasively. Its high resolution has revolutionized the field of optical imaging, having many important applications in preclinical research and clinical diagnosis.
By combining MSOT and FMT in a hybrid system, a unique synergy is established, since MSOT can potentially provide the input needed by FMT to achieve a radical improvement in its imaging performance, not to mention that the simple combination of the molecular information yielded by FMT with the functional and anatomical information yielded by MSOT is certainly useful for biomedical researchers and clinics. Furthermore a FMT/MSOT system will be capable of serving as a cheap diagnostic tool for rheumatoid arthritis (RA), shifting the expensive MRI diagnosis paradigm, and for the first time rendering economically viable the frequent monitoring of this aging-related disease, which is a major cause of mortality in Europe.
The objective of this project is to develop the first hybrid FMT/MSOT system, engineering the optimal tomographic approaches for exploiting the system’s synergies to achieve unprecedented FMT performance. The system’s capacity as a tool for the diagnosis of RA will be tested at the clinic.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- medical and health sciences clinical medicine rheumatology
- engineering and technology medical engineering diagnostic imaging
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
85764 Neuherberg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.