Objective
Inorganic nanomaterials have attracted extensive attention as a result of their potential for a multitude of applications including those related to electronics and catalysis, and as part of sensors in medical diagnosis. Previously, we have described a new technique to generate gold nanoparticles inside the cavity of a ferritin cage protein by first forming a small nanocluster and using it as a seed for particle formation. Unlike previous techniques, this method does not require modification of the protein (e. g. engineering cysteine residues inside the cavity) and therefore has the potential to be used with any nanocage protein. This cage protein universality is a powerful aspect of our technology as the use of various cage proteins could provide synthetic vessels of different sizes and shapes, resulting in nanoparticles with different, and rationally defined, morphologies. Our method provides a second advantage in that the initial nanocluster could be used to seed other metals, resulting in protein-encapsulated, core-shell, dual-metal, nanoparticles. (These two advantages are exploited in Objective 1). Third, our method, by providing presumed universal flexible access to protein cages with different symmetries, sizes, and “handle” attachment sites, could provide, using the power and precision of molecular biology and advances in protein engineering, the opportunity to control the supra-assembly of the nanoparticles, and thus bridge the nano- and micro-scale through a “bottom-up” approach. (This third advantage is exploited in Objective 2) This extremely multi-disciplinary proposal, which marries molecular biology, protein engineering, and nanomaterials, aims to explore and expand upon the flexibility and advantages of our previous work by focusing on these three advantages to generate new hybrid materials.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- natural sciences chemical sciences catalysis
- engineering and technology nanotechnology nano-materials
- natural sciences biological sciences molecular biology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-CIG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
WC2R 2LS London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.