Objective
Plants respond to diverse signals by substantial changes in their morphogenetic plan. Changes in cell shape and size require remodeling of the existing plant cell wall to allow turgor-driven growth to occur. An important question is how plant cell wall remodeling is regulated to accommodate to a changing environment. In our preliminary results, HEAT SHOCK PROTIEN 70-1 (HSP70-1) was identified as novel regulator of cell wall function. Three semi-dominant hsp70-1shou5 alleles were identified as suppressors in fei1fei2 background. The FEI receptor-like kinases regulate cellulose biosynthesis in root tips, etiolated seedlings and seed coat mucilage. HSP70s act as ATPase-dependent chaperones and have diverse functions during plant growth and development and in plant response to different environmental signals. In the proposed research, we will further characterize the effect of the hsp70-1shou5 mutations on cell wall composition and the mechanism of cellulose biosynthesis. The effect of hsp70-1shou5 on plant transcriptome and metabolome will be studied in different developmental contexts (i.e. elongating roots and seed coat). Genetic interactions between hsp70-1shou5 and other cellulose related mutants will be examined. Downstream targets of HSP70-1 will be identified by EMS-induced mutagenesis of fei1fei2hsp70-1shou5 screened for enhancers and suppressors and by yeast two-hybrid screen for HSP70-1 interacting proteins. For a subset of candidate genes identified, their effect on HSP70 activity and cell wall function will be studied. In the proposed research we utilize the hsp70-1shou5 alleles to overcome functional redundancy and assign a new role for HSP70 in the regulation of cell wall remodeling and plant adaptation to changing environment. Improved understanding of the mechanism employed in cell wall remodeling will set the stage for the development of biotechnological tools aimed at the modification of industrial and agricultural traits-of-interest.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry metabolomes
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences genetics RNA transcriptomes
- natural sciences biological sciences genetics mutation
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-CIG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-CIG - Support for training and career development of researcher (CIG)
Coordinator
91904 JERUSALEM
Israel
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.