Obiettivo The most significant advance in cancer therapeutics in recent years has been the introduction of monoclonal antibodies into widespread clinical usage. A consequence of this rapid emergence of antibodies as therapeutics is a lack of trained scientists within the EU with the requisite skills to enable antibody development at a globally competitive pace. The University of Birmingham (UoB) together with the SME SomantiX (SOM) aims to address this need by training the next generation of scientists with the appropriate skills. Together with seven associated partners, we have created an intersectorial EID proposal titled “Vascular-Antibody Mediated Pharmaceutically Induced tumour REsection” or VAMPIRE. The primary aim of the proposal is to train 5 early stage researchers while conducting an internationally competitive oncology research project. VAMPIRE will provide training across a wide range of disciplines involved in the production of antibodies and in their evaluation as therapeutics in animal models of cancer. Training will be provided through an integrated partnership involving all of the partners in the consortium ensuring interdisciplinary and intersectoral experience for the ESRs. The antibodies that we aim to develop will target markers of the tumour vasculature that we have identified previously, including CLEC14A. The commercial partner SOM is a Dutch SME specialized in the development of tumour vascular targeting agents. The findings of this project will be of interest to cancer research and the wider public community. Intellectual property generated by the project is envisioned to be licensed to SOM. Pre-clinical development of the antibodies is envisioned to be carried out via strategic alliances with academic partners and other small biotechnology companies. We view pharmaceutical companies as future business and product development partners in clinical phases of antibody testing. Campo scientifico medical and health sciencesclinical medicineoncology Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2013-ITN - Marie-Curie Action: "Initial Training Networks" Invito a presentare proposte FP7-PEOPLE-2013-ITN Vedi altri progetti per questo bando Meccanismo di finanziamento MC-ITN - Networks for Initial Training (ITN) Coordinatore THE UNIVERSITY OF BIRMINGHAM Contributo UE € 1 459 158,80 Indirizzo Edgbaston B15 2TT Birmingham Regno Unito Mostra sulla mappa Regione West Midlands (England) West Midlands Birmingham Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo May Chung (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (1) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto SOMANTIX BV Paesi Bassi Contributo UE € 8 800,00 Indirizzo PROFESSOR BRONKHORSTLANN 10-92 3723 MB BILTHOVEN Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Laurens Van Der Flier (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato