Cel Tuberculosis (TB) in humans and bovine TB in farm animals are global health problems of immense social and economic importance.Human TB: Mycobacterium tuberculosis (M.tb) is a slowly replicating bacillus that resides intracellularly within phagosomes of macrophages and commonly causes latent infections of the lung and in about 5% of the infected individuals it leads to active disease. Co-infection with M. tuberculosis is estimated in about one-third of HIV-1 infected subjects. Indeed, the risk of developing M. tuberculosis as an opportunistic infection is increased up to 200-fold in HIV-1+ subjects. Drug resistance to HIV-treatment and appearance of multiple-drug resistance (MDR) and off late of Extra-Drug Resistance (XDR) strains of M. tuberculosis, the causative agent of human TB is steadily leading to a hopeless situation as far as the therapy is concerned.Bovine TB: Bovine tuberculosis is caused by the bacterium Mycobacterium bovis, which is closely related to Mycobacterium tuberculosis, the cause of human tuberculosis. M. bovis can be transmitted to humans through the ingestion of unpasteurised milk and milk products as well as aerosols, from infected cows. The introduction of pasteurisation eliminated transmission through contaminated milk and greatly reduced the human health problem1. The principal hosts for bovine tuberculosis are cattle and buffalo, however many other domestic and wild animals can become infected e.g. goats, cervids, pigs, wild boars, dogs, cats, camels, badgers, primates, hares, amongst others. Bovine tuberculosis is found worldwide. All developed countries currently have a TB eradication program in place for many years. These programs have been largely successful; however, incidences are increasing in many countries (e.g. UK, Ireland, France, Austria, Germany).The specific objectives achievable within DEMO-NOPERSIST project are1. Development and evaluation of prototype test kits for active human TB (LIONEX, SME). This test shall be the World’s first blood test for discriminating latent from active TB in humans.2. Development and evaluation of prototype test kits for active Bovine TB (PRIONICS, SME)3. To develop marketable, improved diagnostic products for human and bovine TB within a period of 2-3 years .Thus, both human and bovine active TB tests are directly linked to the NOPERSIST project and shall be an excellent demonstration of a Res4SME project NOPERSIST. Dziedzina nauki natural sciencesbiological scienceszoologymammalogyprimatologymedical and health sciencesclinical medicinepneumologytuberculosisagricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandrymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistancemultidrug resistanceengineering and technologymedical engineeringmedical laboratory technologylaboratory samples analysis Program(-y) FP7-SME - Specific Programme "Capacities": Research for the benefit of SMEs Temat(-y) SME-2013-3 - Demonstration activity Zaproszenie do składania wniosków FP7-SME-2013 Zobacz inne projekty w ramach tego zaproszenia System finansowania CP - Collaborative project (generic) Koordynator LIONEX GMBH Wkład UE € 247 920,00 Adres Salzdahlumer Strasse 196 38126 Braunschweig Niemcy Zobacz na mapie Region Niedersachsen Braunschweig Braunschweig, Kreisfreie Stadt Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Mahavir Singh (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (3) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko PRIONICS AG Szwajcaria Wkład UE € 47 280,00 Adres WAGISTRASSE 27 A 8952 SCHLIEREN Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Alex Raeber (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych UNIVERSITA DEGLI STUDI DI FIRENZE Włochy Wkład UE € 66 400,00 Adres Piazza San Marco 4 50121 Florence Zobacz na mapie Region Centro (IT) Toscana Firenze Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Mario Milco D'elios (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Food and Environment Research Agency Zjednoczone Królestwo Wkład UE € 10 400,00 Adres Area 1A, Nobel House, Smith Square 17 SW1P 3JR LONDON Zobacz na mapie Region London Inner London — West Camden and City of London Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Lucinda Cranham (Mrs.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych
