Objetivo Currently, clinical diagnosis and monitoring of bladder cancer (BC) relies on invasive, highly costly cystoscopy. Additionally, due to high recurrence rates BC treatment is associated with frequent follow-up of patients, making BC one of the most costly types of cancer in terms of management cost. Thus there is a clear clinical need for the development of new approaches for early detection of recurrence and progression.Our proposal is based on the identification of novel biomarkers (BM) for BC recurrence and progression in urine and powerful technological platforms as extensive foreground work of the involved partners in the framework of FP7 EU projects DECanBio and GENINCA. The objective of TransBioBC is to translate this foreground work in the field of BC and to specifically employ the involved technologies (CE-MS and micro-ELISA), represented by the participating SMEs, for the development of non-invasive urine tests for routine monitoring of BC recurrence and progression. Our project uniquely integrates leading BC clinical experts with experts on proteome analysis and high throughput immunoassay development in an implementation-oriented workflow. Strict monitoring of assay analytical performance, and properly collected and well characterized clinical samples from existing sufficiently powered BC cohorts are combined with in-depth knowledge of regulatory requirements, analysis approaches to define added value and well designed business plans including multi-stakeholder dissemination and exploitation plans.Collectively, TransBioBC will provide strong evidence for utility of the new BM directly in BC clinical management and as a secondary aim for usage in clinical trials and drug development. Ámbito científico medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomicsmedical and health sciencesclinical medicineoncologybladder cancerengineering and technologymedical engineeringmedical laboratory technologylaboratory samples analysis Programa(s) FP7-HEALTH - Specific Programme "Cooperation": Health Tema(s) HEALTH.2013.0-1 - Boosting the translation of health research projects' results into innovative applications for health Convocatoria de propuestas FP7-HEALTH-2013-INNOVATION-2 Consulte otros proyectos de esta convocatoria Régimen de financiación CP-FP - Small or medium-scale focused research project Coordinador IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON Aportación de la UE € 760 964,80 Dirección SORANOU EFESIOU 4 115 27 Athina Grecia Ver en el mapa Región Αττική Aττική Κεντρικός Τομέας Αθηνών Tipo de actividad Research Organisations Contacto administrativo Dimitris Raptis (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (3) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo MOSAIQUES DIAGNOSTICS GMBH Alemania Aportación de la UE € 1 119 089,00 Dirección ROTENBURGER STRASSE 20 30659 Hannover Ver en el mapa Región Niedersachsen Hannover Region Hannover Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Harald Mischak (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos DIAGNOSWISS SA Suiza Aportación de la UE € 831 344,00 Dirección ZI LES ILETTES SECTEUR 4 1870 MONTHEY Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Frédéric Reymond (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III España Aportación de la UE € 548 960,80 Dirección C MELCHOR FERNANDEZ ALMAGRO 3 28029 Madrid Ver en el mapa Región Comunidad de Madrid Comunidad de Madrid Madrid Tipo de actividad Research Organisations Contacto administrativo Lilit Manukyan (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos
